10107409001

Mitomycin C

crystalline powder, 98%, pkg of 2 mg

• 동의어(들): Mitomycin C
• 실험식(Hill 표기법): C₁₅H₁₈N₄O₅
• CAS Number: 50-07-7
• Molecular Weight: 334.33
• MDL number: MFCD00078109
• UNSPSC 코드: 12352207

속성

• Quality Level: 100
• 분석: 98%
• 양식: crystalline powder
• 분자량: 334.3
• 포장: pkg of 2 mg
• 제조업체/상표: Roche
• 항생제 활성 스펙트럼: Gram-negative bacteria; Gram-positive bacteria
• 동작 모드: DNA synthesis | interferes
• 저장 온도: 2-8°C
• SMILES string: N21[C@]([C@H]4N[C@H]4C2)([C@@H](C3=C1C(=O)C(=C(C3=O)N)C)COC(=O)N)OC
• InChI: 1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
• InChI key: NWIBSHFKIJFRCO-WUDYKRTCSA-N

설명

일반 설명

Mitomycin C is an antitumor antibiotic.

애플리케이션

Mitomycin C has been used:

• to cease mitosis
• in phosphate buffer saline (PBS) for inactivation and plating mouse embryonic fibroblasts (MEFs)
• as mutagen in mutagenicity assay

Mitomycin C is used as an inhibitor for studies of cell-free protein biosynthesis. It also inhibits DNA synthesis. It has been used as a genotoxic agent for tumor cells.

생화학적/생리학적 작용

Mitomycin C (MMC) acts as a prototype for drugs with bioreductive alkylation. It is mainly found to be active under anaerobic conditions. MMC exhibits a vast clinical antitumor spectrum effectively in gastric, pancreatic and breast cancer.

기타 정보

For life science research only. Not for use in diagnostic procedures.

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H300,H351
• 예방조치 성명서: P201 - P264 - P280 - P301 + P310 + P330 - P308 + P313 - P501
• Hazard Classifications: Acute Tox. 2 Oral - Carc. 2
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): does not flash
• Flash Point (°C): does not flash