MAB2638

Anti-Integrin beta7 Antibody, clone TN114

clone TN114, from hamster(Armenian)

• 동의어(들): integrin, beta 7, integrin beta 7 subunit, Gut homing receptor beta subunit
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: hamster (Armenian)
• Quality Level: 100
• 항체 형태: purified antibody
• 항체 생산 유형: primary antibodies
• 클론: TN114, monoclonal
• 종 반응성: human
• 기술: flow cytometry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable
• 동형: IgG
• NCBI 수납 번호: NP_000880.1
• UniProt 수납 번호: P26010
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ITGB7(3695)

설명

일반 설명

Integrin beta7 is an adhesion molecule belonging to the integrin beta chain family. It forms heterodimers with the alpha subunit, most notably the integrin alpha4 and alphaE subunits, functioning to mediate migration and homing of lymphocytes to the gut-associated lymphoid tissue (GALT). The heterodimer formed with alpha4, α4β7, is specifically involved in the homing and migration of lymphocytes to the gut, while αEβ7 is involved in the binding of T lymphocytes to epithelial cells and is induced by TGFβ1. Integrin beta7 has been observed in several different leukocyte lines.

특이성

The antibody recognizes Integrin beta7.

면역원

Epitope: Unknown

Purified human integrin beta7 protein.

애플리케이션

Anti-Integrin beta7 Antibody, clone TN114 is an antibody against Integrin beta7 for use in FC, IP, IH.

Research Category
Cell Structure

Research Sub Category
Integrins

품질

Evaluated by Flow Cytometry in human PBMC′s.

Flow Cytometry Analysis: 1 µg/mL of this antibody detected Integrin beta7 on human PBMC′s.

표적 설명

~ 86 kDa

물리적 형태

Format: Purified

Protein G Purified

Purified armenian hamster monoclonal IgG in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Human peripheral blood mononuclear cells (PBMC′s).

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable