추천 제품
제품명
Anti-Integrin β1 Antibody, clone HB1.1, clone HB1.1, Chemicon®, from mouse
생물학적 소스
mouse
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
HB1.1, monoclonal
종 반응성
human, pig
제조업체/상표
Chemicon®
기술
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
동형
IgG1κ
적합성
not suitable for activity/function inhibition
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... ITGB1(3688)
특이성
Reacts with beta-1 subunit of VLA integrins
애플리케이션
Anti-Integrin β1 Antibody, clone HB1.1 detects level of Integrin β1 & has been published & validated for use in FC, IP, WB, IH.
Immunoprecipitation of VLA integrins from lysate of 10E6 cell equivalent requires 2 μg of MAB2000.
Flow cytometry: 10 μg/mL
Western blot
Immunohistochemistry in frozen tissue samples: 5 μg/mL
Induction of cell aggregation: 10 μg/mL. MAB2000 is a potent stimulator of cell aggregation tested in U937, Jurkat and human peripheral blood lymphocytes.
MAB2000 does not affect VLA integrin-mediated cell adhesion to matrix proteins.
Optimal working dilutions must be determined by end user.
Flow cytometry: 10 μg/mL
Western blot
Immunohistochemistry in frozen tissue samples: 5 μg/mL
Induction of cell aggregation: 10 μg/mL. MAB2000 is a potent stimulator of cell aggregation tested in U937, Jurkat and human peripheral blood lymphocytes.
MAB2000 does not affect VLA integrin-mediated cell adhesion to matrix proteins.
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
결합
Replaces: 04-1109
물리적 형태
Format: Purified
Purified immunoglobulin from Protein A chromatography. Liquid in 0.02M PB pH 7.6, 0.25M NaCl with 0.1% sodium azide.
저장 및 안정성
Maintain at 2-8°C for up to 6 months after date of receipt.
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Hypersialylation of beta1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility.
Seales, EC; Jurado, GA; Brunson, BA; Wakefield, JK; Frost, AR; Bellis, SL
Cancer Research null
PtdIns(3,4,5)P3 regulates spindle orientation in adherent cells.
Toyoshima, F; Matsumura, S; Morimoto, H; Mitsushima, M; Nishida, E
Developmental Cell null
Hyposialylation of integrins stimulates the activity of myeloid fibronectin receptors.
Semel, AC; Seales, EC; Singhal, A; Eklund, EA; Colley, KJ; Bellis, SL
The Journal of Biological Chemistry null
Pig chondrocyte xenoimplants for human chondral defect repair: an in vitro model.
Fuentes-Boquete, Isaac, et al.
Wound Repair and Regeneration, 12, 444-452 (2004)
Mechanical control of cAMP signaling through integrins is mediated by the heterotrimeric Galphas protein.
Francis J Alenghat,Jessica D Tytell,Charles K Thodeti,Alexandrine Derrien,Donald E Ingber
Journal of Cellular Biochemistry null
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