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Merck
모든 사진(1)

주요 문서

AB9680

Sigma-Aldrich

Anti-GABA A Receptor β 1 Antibody

Chemicon®, from rabbit

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

affinity purified immunoglobulin

항체 생산 유형

primary antibodies

클론

polyclonal

정제법

affinity chromatography

종 반응성

human, rat, mouse

제조업체/상표

Chemicon®

기술

western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... GABRB1(2560)

특이성

GABAA Receptor beta 1 subunit. The antibody recognizes a protein of ~55 kDa corresponding to GABAA Receptor beta 1 subunit in lysates from rat cerebellum and cortex.

면역원

Fusion protein from the Cytosolic loop of rat the GABAA Receptor beta 1 subunit.

애플리케이션

Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
This Anti-GABA A Receptor β 1 Antibody is validated for use in WB for the detection of GABA A Receptor β 1.
Western blot: 1:1,000.

Optimal working dilutions must be determined by the end user.

결합

Replaces: AB5451

물리적 형태

Affinity purified immunoglobulin. Liquid in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.

저장 및 안정성

Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self defrosting freezer.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2


시험 성적서(COA)

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문서 라이브러리 방문

R W Olsen et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 4(5), 1469-1480 (1990-03-01)
The major type of receptor for the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), called the GABAA receptor, is a member of a gene superfamily of ligand-gated ion channels. This receptor is a hetero-oligomeric protein composed of several distinct polypeptide types (alpha
Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABAA receptor gamma2-subunit.
Ogris W, et al.
Biochemical Pharmacology, 68, 1621-1629 (2004)
Angelika Pöltl et al.
Journal of neurochemistry, 87(6), 1444-1455 (2004-01-10)
In cerebellum, 13 different GABA(A) receptor subunits are expressed. The number of different receptor subtypes formed in this tissue, their subunit composition and their quantitative importance so far has not been determined. In the present study, immunodepletion by immunoaffinity chromatography
A K Mehta et al.
Brain research. Molecular brain research, 67(1), 194-199 (1999-04-02)
The anti-alpha1 antibody elicited higher immunoprecipitation (%) values of the [3H]flunitrazepam and [3H]muscimol binding activity in the rat cerebellum vs. cerebral cortex, whereas immunoprecipitation values for [3H]Ro 15-4513 and [3H]zolpidem were comparable in these brain regions. Chronic ethanol administration neither
Alejandra Cabello-Arreola et al.
Genes, 11(3) (2020-03-04)
Suicide is a major public health concern; nevertheless, its neurobiology remains unknown. An area of interest in suicide research is the dorsolateral prefrontal cortex (DLPFC). We aimed to identify altered proteins and potential biological pathways in the DLPFC of individuals

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