AB3749

Anti-mGCM1 Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): GCM motif protein 1, Glial cells missing homolog 1, chorion-specific transcription factor GCMa, glial cells missing homolog a
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human
• 기술: western blot: suitable
• 입력: sample type pancreatic stem cell(s); sample type neural stem cell(s)
• UniProt 수납 번호: P70348
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... GCM1(8521)

설명

일반 설명

GCM1 is a DNA binding protein with a GCM motif (glial cell missing motif) that is a key transcription factor for determining the fate of stem cells within the nervous system, in addition to being critical for placental development. This protein binds to the GCM motif (A/G)CCCGCAT, a novel sequence among known targets of DNA binding proteins. The N-terminal DNA-binding domain confers the unique DNA binding activity of this protein. Current studies indicate that the introduction of the mouse GCM1 gene in cultured cells from embryonic brains resulted in the induction of an astrocyte lineage.

특이성

Comparison of sequence homology suggests that this antibody will also react in mouse and rat; however, reactivity to other species has not been tested.

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptided selected from the C-terminal region mouse GCM1.

면역원

Epitope: C-terminus

Synthetic GCM1 peptide, a.a. 401-418.

애플리케이션

Research Category
Stem Cell Research

Research Sub Category
Neural Stem Cells

This Anti-mGCM1 Antibody is validated for use in WB for the detection of mGCM1.

품질

Routinely evaluated by western blot on HEK-293 lysates.

Western Blotting: Recommended working dilutions are 1:1000 – 1:2500.

표적 설명

50 kDa

물리적 형태

Peptide affinity purified

Purified rabbit polyclonal antibody in buffer containing PBS with 0.09% sodium azide.

저장 및 안정성

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable