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Merck
모든 사진(1)

주요 문서

AB3081

Sigma-Aldrich

Anti-Na+/H+ Exchanger-1 Antibody

Chemicon®, from rabbit

동의어(들):

NHE1

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모든 사진(1)

About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

100

항체 형태

affinity purified immunoglobulin

항체 생산 유형

primary antibodies

클론

polyclonal

정제법

affinity chromatography

종 반응성

human, rat, bovine, mouse, pig

제조업체/상표

Chemicon®

기술

ELISA: suitable
western blot: suitable

NCBI 수납 번호

NM_003047.2

UniProt 수납 번호

P19634

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... SLC9A1(6548)

특이성

Recognizes Na+/H+ Exchanger 1 (NHE1). The immunogen peptide shows no significant homology with other NHE isoforms (NHE2-5).

면역원

A 22 aa peptide within the cytoplasmic, C-terminal domain of rat NHE1, coupled to KLH.

애플리케이션

Detect Na+/H+ Exchanger-1 using this Anti-Na+/H+ Exchanger-1 Antibody validated for use in ELISA & WB.
Western blot: 1-10 μg/mL using Chemiluminescence technique.



ELISA: 1:100,000 using 50-100 ng control peptide per well.

Optimal working dilutions must be determined by end user.

표적 설명

91 kDa

물리적 형태

Affinity Purified immunoglobulin. Liquid in PBS and 0.1% BSA .

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Malignant gliomas display altered plasma membrane potential and pH regulation--interaction with Tc-99m-MIBI and Tc-99m-Tetrofosmin uptakes.
N Perek, D Denoyer, F Dubois, F Koumanov
General Physiology and Biophysics null
Bryan J Feger et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 305(10), R1182-R1189 (2013-09-21)
The myocardial Na(+)/H(+) exchanger-1 (NHE1) plays a major role in regulation of intracellular pH, and its upregulation has been implicated in increased ischemia-reperfusion injury and other pathologies. Hydrogen peroxide (H2O2) increases NHE1 activity acutely via ERK1/2 signaling. Chronic strenuous exercise
J Orlowski et al.
The Journal of biological chemistry, 267(13), 9331-9339 (1992-05-05)
Biochemical and pharmacological data support the existence of multiple forms of the Na/H exchanger (NHE). Two isoforms, termed NHE-1 and NHE-2, have recently been isolated from rabbit ileal villus epithelial cells (Tse, C. M., Ma, A. I., Yang, V. W.
Danny Christiansen et al.
Acta physiologica (Oxford, England), 231(3), e13580-e13580 (2020-11-23)
To assess how blood-flow-restricted (BFR) interval-training affects the capacity of the leg muscles for pH regulation during dynamic exercise in physically trained men. Ten men (age: 25 ± 4y; V˙O2max : 50 ± 5 mL∙kg-1 ∙min-1 ) completed a 6-wk interval-cycling intervention (INT) with one
C H Yun et al.
The American journal of physiology, 269(1 Pt 1), G1-11 (1995-07-01)
Na+/H+ exchangers are integral plasma membrane proteins that exchange extracellular Na+ for intracellular H+ with a stoichiometry of one for one. They are inhibitable by the diuretic amiloride and have multiple cellular functions, including intracellular pH homeostasis, cell volume control
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