추천 제품
Quality Level
제품 라인
NovaSyn® TG
Novabiochem®
양식
beads
반응 적합성
reaction type: Fmoc solid-phase peptide synthesis
제조업체/상표
Novabiochem®
응용 분야
peptide synthesis
작용기
alcohol
저장 온도
2-30°C
일반 설명
NovaSynTG hydroxy resin is a composite of low cross-linked polystyrene and 3000-4000 M.W. polyethylene glycol, in which the ends of the PEG chains have been functionalized with hydroxyl groups. The 130 μm beads have a narrow size distribution, high diffusion rates and excellent swelling across a wide range of solvents from toluene to water [1,2,3], making them ideally suited to the synthesis of serial and parallel libraries by organic solid phase synthesis. This support has been used for the solid phase immobilization of carboxylic acids [4,5,6,7,8,9], with cleavage by saponification with dilute aq. NaOH.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Literature references
[1] W. Rapp, et al. in ′Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium′, R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 205.
[2] L. Zhang, et al. in ′Peptides 1990, Proc. 21st European Peptide Symposium′, E. Giralt & D. Andreu (Eds), ESCOM, Leiden, 1990, pp.196.
[3] E. Bayer (1991) Angew. Chem. Int. Ed. Engl., 30, 113.
[4] M. Hiroshige, et al. (1995) Tetrahedron Lett., 36, 4567.
[5] M. C. Fagnola, et al. (1997) Tetrahedron Lett., 38, 2307.
[6] D. Fancelli, et al. (1997) Tetrahedron Lett., 38, 2311.
[7] M. Patek, et al. (1995) Tetrahedron Lett., 36, 2227.
[8] V. Krchnak, et al. (1995) Tetrahedron Lett., 36, 6193.
[9] A. K. Szardenings & T. S. Burkoth (1997)Tetrahedron, 53, 6573.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Literature references
[1] W. Rapp, et al. in ′Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium′, R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 205.
[2] L. Zhang, et al. in ′Peptides 1990, Proc. 21st European Peptide Symposium′, E. Giralt & D. Andreu (Eds), ESCOM, Leiden, 1990, pp.196.
[3] E. Bayer (1991) Angew. Chem. Int. Ed. Engl., 30, 113.
[4] M. Hiroshige, et al. (1995) Tetrahedron Lett., 36, 4567.
[5] M. C. Fagnola, et al. (1997) Tetrahedron Lett., 38, 2307.
[6] D. Fancelli, et al. (1997) Tetrahedron Lett., 38, 2311.
[7] M. Patek, et al. (1995) Tetrahedron Lett., 36, 2227.
[8] V. Krchnak, et al. (1995) Tetrahedron Lett., 36, 6193.
[9] A. K. Szardenings & T. S. Burkoth (1997)Tetrahedron, 53, 6573.
결합
Replaces: 01-64-0096
분석 메모
Color (visual): white to amber to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
130 µm beads
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
130 µm beads
법적 정보
NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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