557450

Ruthenium Red

A blocker of transmembrane Ca²⁺ fluxes (IC₅₀ = 7 µM) that attenuates capsaicin-induced cation channel opening.

• 동의어(들): Ruthenium Red, Ammoniated Ruthenium Oxychloride, RR
• Linear Formula: [(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆
• CAS Number: 12790-48-6
• MDL number: MFCD00270912
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 설명: Merck USA index - 14, 8300
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated
• 색상: red-black
• solubility: ammonia: soluble; water: soluble
• 배송 상태: ambient
• 저장 온도: 10-30°C

설명

일반 설명

A blocker of transmembrane Ca²⁺ fluxes (IC₅₀ = 7 µM) that attenuates capsaicin-induced cation channel opening. Inhibits Ca²⁺-induced Ca²⁺ release from ryanodine-sensitive intracellular Ca²⁺ stores. Inhibits K⁺-stimulated catecholamine secretion (IC₅₀ = 6 µM).

생화학적/생리학적 작용

Cell permeable: no

Primary Target
Blocker of transmembrane Ca2+ fluxes

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 7 µM in blocking transmembrane Ca2+ fluxes; 6 µM inhibiting K+-stimulated catecholamine secretion

경고

Toxicity: Harmful (C)

기타 정보

Merck Index 13, 8379.
Phillippe, M. and Basa, A. 1996. Biochem. Biophys. Res. Commun. 221, 656.
Buratti, R., et al. 1995. Biochem. Biophys. Res. Commun. 213, 1082.
Hamilton, M.G. and Lundy, P.M. 1995. J. Pharmacol. Exp. Ther. 273, 940.
Gomis, A., et al. 1994. Biochem. Pharmacol. 47, 225.
Stjame, P., et al. 1994. Acta Otolaryngol. 114, 651.
Ma, J. 1993. J. Gen. Physiol.102, 1031.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable