444225

MMP-3 Inhibitor II

The MMP-3 Inhibitor II, also referenced under CAS 161314-17-6, controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• 동의어(들): MMP-3 Inhibitor II, N-Isobutyl-N-(4-methoxyphenylsulfonyl)-glycylhydroxamic Acid, NNGH
• 실험식(Hill 표기법): C₁₃H₂₀N₂O₅S
• CAS Number: 161314-17-6
• Molecular Weight: 316.37
• MDL number: MFCD02179370
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (TLC)
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 색상: white
• solubility: DMSO: 30 mg/mL; ethanol: 8 mg/mL
• 배송 상태: ambient
• 저장 온도: 10-30°C
• SMILES string: [S](=O)(=O)(N(CC(C)C)CC(=O)NO)c1ccc(cc1)OC
• InChI: 1S/C13H20N2O5S/c1-10(2)8-15(9-13(16)14-17)21(18,19)12-6-4-11(20-3)5-7-12/h4-7,10,17H,8-9H2,1-3H3,(H,14,16)
• InChI key: JIRXORZYIXSWOB-UHFFFAOYSA-N

설명

일반 설명

A cell-permeable, potent inhibitor of human MMP-3 (stromelysin; K_i = 130 nM).

A potent and cell-permeable inhibitor of human MMP-3 (K_i = 130 nM).

생화학적/생리학적 작용

Cell permeable: yes

Primary Target
human MMP-3

Product does not compete with ATP.

Reversible: no

Target K_i: 130 nM against human MMP-3

경고

Toxicity: Standard Handling (A)

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

기타 정보

Kato, N., et al. 2002. Genome Informatics13, 272.
MacPherson, L.J., et al. 1997. J. Med. Chem. 40, 2525.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable