추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified antibody
항체 생산 유형
primary antibodies
클론
C3, monoclonal
종 반응성
human, rat, mouse
제조업체/상표
Upstate®
기술
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
동형
IgG1
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... MAPT(4137)
mouse ... Mapt(17762)
rat ... Mapt(29477)
특이성
cleaved-Tau
면역원
Synthetic peptide corresponding to amino acids 412-421(CSSTGSIDMVD) of human Tau with a Cys at the N-terminal end
애플리케이션
Anti-cleaved-Tau (Asp421) Antibody, clone C3 is an antibody against cleaved-Tau (Asp421) for use in IP, WB, IH.
품질
routinely evaluated by immunoblot on Tau fusion protein cleaved by Caspase 3 (Catalog #14-264)
표적 설명
50-70kDa
물리적 형태
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol
Format: Purified
법적 정보
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Modeling tau polymerization in vitro: a review and synthesis.
Gamblin, T Chris, et al.
Biochemistry, 42, 15009-15017 (2003)
F Biundo et al.
Translational psychiatry, 7(8), e1198-e1198 (2017-08-09)
TAU mutations are genetically linked to fronto-temporal dementia (FTD) and hyper-phosphorylated aggregates of Tau form neurofibrillary tangles (NFTs) that constitute a pathological hallmark of Alzheimer disease (AD) and FTD. These observations indicate that Tau has a pivotal role in the
Urmi Sengupta et al.
Methods in molecular biology (Clifton, N.J.), 1779, 113-146 (2018-06-11)
An increasing number of studies have demonstrated the existence of multiple conformational entities of tau, as have been observed for prion protein. We have developed and optimized techniques to isolate and study oligomeric tau strains both in vitro and ex
Argyrophilic grain disease is a sporadic 4-repeat tauopathy
Togo, Takashi, et al
Journal of Neuropathology and Experimental Neurology, 61, 547-556 (2002)
Michelle A Utton et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(15), 6394-6400 (2002-08-02)
We demonstrate that the microtubule-associated protein tau, in the form of enhanced green fluorescent protein (EGFP) tau, is transported along axons of neurons in culture in the slow component of axonal transport with a speed comparable with that previously measured
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