추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
정제법
affinity chromatography
종 반응성
human, mouse, rat
제조업체/상표
Upstate®
기술
ELISA: suitable
western blot: suitable
동형
IgG
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
phosphorylation (pTyr412)
유전자 정보
human ... ABI1(10006)
mouse ... Abi1(11308)
rat ... Abi1(79249)
특이성
Other species have not been tested.
Recognizes both Abl and BCR-Abl when phosphorylated on tyrosine residue corresponding to Tyr412 in Abl.
면역원
KLH-conjugated peptide corresponding to amino acid region encompassing human c-Abl Tyr412.
애플리케이션
Research Category
Signaling
Signaling
Research Sub Category
Cytoskeletal Signaling
General Post-translation Modification
Cytoskeletal Signaling
General Post-translation Modification
This Anti-phospho-Abl (Tyr412) Antibody is validated for use in ELISA, WB for the detection of phospho-Abl (Tyr412).
품질
Routinely evaluated by immunoblot.
표적 설명
145 kDa
물리적 형태
ImmunoAffinity Purified
법적 정보
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Wenjing Tao et al.
The Journal of biological chemistry, 289(31), 21463-21472 (2014-06-14)
Jak2 is involved in cytokine growth factor-stimulated signal transduction, but the mechanism of its activation is largely unknown. Here, we investigated Jak2 activation in a normal hematopoietic cell line, 32D mouse myeloid cells. The bimolecular fluorescence complementation studies showed that
Phosphoproteomic analysis of AML cell lines identifies leukemic oncogenes
Walters, Denise K, et al
Leukemia Research, 30, 1097-1104 (2006)
Phosphotyrosine mapping in Bcr/Abl oncoprotein using phosphotyrosine-specific immonium ion scanning
Steen, Hanno, et al
Molecular and Cellular Proteomics, 2, 138-145 (2003)
Jae Yeon Kim et al.
Cell reports, 30(1), 187-201 (2020-01-09)
More than one-half of the interneurons in a mouse olfactory bulb (OB) develop during the first week after birth and predominantly connect to excitatory tufted cells near the superficial granule cell layer (sGCL), unlike late-born interneurons. However, the molecular mechanisms
John Rush et al.
Nature biotechnology, 23(1), 94-101 (2004-12-14)
Tyrosine kinases play a prominent role in human cancer, yet the oncogenic signaling pathways driving cell proliferation and survival have been difficult to identify, in part because of the complexity of the pathways and in part because of low cellular
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