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Merck
모든 사진(1)

주요 문서

04-118

Sigma-Aldrich

Anti-acetyl-Histone H4 (Lys5) Antibody, rabbit monoclonal

culture supernatant, Upstate®

동의어(들):

H4K5Ac, Histone H4 (acetyl K5)

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

culture supernatant

항체 생산 유형

primary antibodies

클론

monoclonal

종 반응성

vertebrates, human

제조업체/상표

Upstate®

기술

western blot: suitable

동형

IgG

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

acetylation (Lys5)

유전자 정보

human ... H4C1(8359)

특이성

Recognizes Histone H4 when acetylated on Lys5.

면역원

Peptide corresponding to Histone H4 containing the sequence [GRG-AcK-GGK] on which Lys5 is acetylated.

애플리케이션

Detect acetyl-Histone H4 (Lys5) using this Anti-acetyl-Histone H4 (Lys5) Antibody, rabbit validated for use in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones

품질

Routinely evaluated by immunoblot.

표적 설명

11kDa

물리적 형태

100 μL of rabbit monoclonal IgG cell culture supernatant in 0.1% sodium azide.

저장 및 안정성

2 years at -20°C from date of shipment

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Haipeng Guan et al.
Nature, 620(7974), 669-675 (2023-07-20)
Context-dependent dynamic histone modifications constitute a key epigenetic mechanism in gene regulation1-4. The Rpd3 small (Rpd3S) complex recognizes histone H3 trimethylation on lysine 36 (H3K36me3) and deacetylates histones H3 and H4 at multiple sites across transcribed regions5-7. Here we solved
Zengxuan An et al.
The Plant journal : for cell and molecular biology, 103(3), 1010-1024 (2020-04-24)
Histones are highly basic proteins involved in packaging DNA into chromatin, and histone modifications are fundamental in epigenetic regulation in eukaryotes. Among the numerous chromatin modifiers identified in Arabidopsis (Arabidopsis thaliana), MORF-RELATED GENE (MRG)1 and MRG2 have redundant functions in
Sepehr Ehsani et al.
Journal of molecular biology, 422(4), 556-574 (2012-06-13)
We recently documented the co-purification of members of the LIV-1 subfamily of ZIP (Zrt-, Irt-like Protein) zinc transporters (LZTs) with the cellular prion protein (PrP(C)) and, subsequently, established that the prion gene family descended from an ancestral LZT gene. Here
S Ono et al.
Journal of experimental & clinical cancer research : CR, 21(3), 377-382 (2002-10-19)
Acetylation of core histones is closely linked to transcriptional activation of various genes. The acetylation levels of nucleosomal histones can be modified through a balance of histone acetyltransferases and deacetylases. To elucidate the role of histone acetylation in human gastric
RSC exploits histone acetylation to abrogate the nucleosomal block to RNA polymerase II elongation.
Carey, Michael, et al.
Molecular Cell, 24, 481-487 (2006)

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