추천 제품
Grade
certified reference material
Quality Level
양식
liquid
특징
Snap-N-Spike®/Snap-N-Shoot®
포장
ampule of 1 mL
제조업체/상표
Cerilliant®
농도
1.0 mg/mL in methanol
기술
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
응용 분야
forensics and toxicology
형식
single component solution
저장 온도
−20°C
SMILES string
O=NN1CCCC1c2cccnc2
InChI
1S/C9H11N3O/c13-11-12-6-2-4-9(12)8-3-1-5-10-7-8/h1,3,5,7,9H,2,4,6H2
InChI key
XKABJYQDMJTNGQ-UHFFFAOYSA-N
일반 설명
N′-Nitrosonornicotine, also known as NNN, is a nitrosamine and potential carcinogen found in a variety of tobacco products including snuff, cigarettes, chewing tobacco, and cigars. Certified Spiking Solutions® are suitable for use in nicotine testing or environmental monitoring by LC-MS/MS or GC/MS.
법적 정보
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTIONS is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
표적 기관
Eyes
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point (°F)
51.8 °F - closed cup
Flash Point (°C)
11.0 °C - closed cup
가장 최신 버전 중 하나를 선택하세요:
이미 열람한 고객
Jian-Min Yuan et al.
Carcinogenesis, 32(9), 1366-1371 (2011-07-08)
N'-Nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) are tobacco-specific nitrosamines. NNN and NNK can induce cancers of the esophagus and lung, respectively, in laboratory animals, but data on human esophageal cancer are lacking. The association between levels of NNN and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL)
Michael Urban et al.
Journal of analytical toxicology, 33(5), 260-265 (2009-08-13)
The tobacco-specific nitrosamine N'-nitrosonornicotine (NNN) is carcinogenic to humans (IARC Group 1). Assessing the tobacco smoke-related exposure to NNN by suitable biomarkers is of interest for risk evaluation. Recently, NNN and NNN-N-glucuronide have been quantified in urine of smokers. However
N-Nitrosamines (15 listings): N-Nitrosonornicotine.
Report on carcinogens : carcinogen profiles, 12, 320-321 (2011-08-24)
Irina Stepanov et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17(4), 945-948 (2008-04-10)
Specific biomarkers of tobacco carcinogen uptake are critical for investigations of the role of tobacco smoke exposure in human cancers. Two new biomarkers of human exposure to tobacco-specific carcinogens have been recently developed by our research group: urinary N'-nitrosonornicotine (NNN)
Karen H Watanabe et al.
Regulatory toxicology and pharmacology : RTP, 55(2), 123-133 (2009-06-23)
The manner in which humans smoke cigarettes is an important determinant of smoking risks. Of the few investigators that have predicted cancer risks from smoking on a chemical-specific basis, most used mainstream cigarette smoke (MCS) carcinogen emissions obtained via machine
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