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모든 사진(1)

주요 문서

999992P

Avanti

16:0 Diether PC

Avanti Research - A Croda Brand 999992P, powder

동의어(들):

1,2-di-O-hexadecyl-sn-glycero-3-phosphocholine

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About This Item

실험식(Hill 표기법):
C40H84NO6P
CAS Number:
Molecular Weight:
706.07
MDL number:
UNSPSC 코드:
51191904
NACRES:
NA.25

양식

powder

포장

pkg of 1 × 10 mg (999992P-10mg)

제조업체/상표

Avanti Research - A Croda Brand 999992P

지질 유형

phospholipids
cardiolipins

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCCCCCC)COCCCCCCCCCCCCCCCC)=O

InChI

1S/C40H84NO6P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-35-44-38-40(39-47-48(42,43)46-37-34-41(3,4)5)45-36-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h40H,6-39H2,1-5H3

InChI key

MWTIGLPPQBNUFP-UHFFFAOYSA-N

일반 설명

16:0 Diether PC (phosphocholine) is a zwitterionic lipid having choline as the alcohol moiety, attached to the phosphate group. It has two hexadecane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds.

애플리케이션

16:0 Diether PC or 1,2-di-O-hexadecyl-sn-glycero-3-phosphocholine might be used:
  • to study the miscibility and phase behavior of the cationic 1,2-dipalmitoyl-sn-glycero-3-ethylphosphocholine (EDPPC)
  • in unilamellar vesicles to study glycolipid transfer protein (GLTP)-mediated transfer of anthrylvinyl-galactosylceramide (AV-GalCer) from different ether phospholipid matrices
  • as a non-ladderane phosphocholine (PC) lipid reference sample in reversed-phase liquid chromatography (LC) method to separate PC lipids
  • to prepare large phospholipid bicelles in order to determine the three-dimensional backbone structure of the transmembrane domain of Vpu from human immunodeficiency virus (HIV)-1 by solid-state nuclear magnetic resonance (NMR) spectroscopy

생화학적/생리학적 작용

Ether glycerolipids serve as membrane molecules and cellular mediators. Ether linked phospholipids act as precursors for important signaling molecules. 16:0 Diether PC (phosphocholine) is known to interdigitate even in the absence of chemical inducers or pressure.

포장

5 mL Amber Glass Screw Cap Vial (999992P-10mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

이미 열람한 고객

Ether-linked lipids and their bioactive species
Biochimica et Biophysica Acta - Biomembranes, 9(2), 245-276 (2008)
Three-dimensional structure of the transmembrane domain of Vpu from HIV-1 in aligned phospholipid bicelles
Park SH, et al.
Biophysical Journal, 91(8), 3032-3042 (2006)

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