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Merck
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860636P

Avanti

Glucosyl(β) Sphingosine-d5

Avanti Research™ - A Croda Brand

동의어(들):

D-glucosyl-β-1,1′-D-erythro-sphingosine-d5

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C24H42D5NO7
CAS Number:
1347831-14-4
Molecular Weight:
466.66
MDL number:
MFCD35071465
UNSPSC 코드:
12352211
NACRES:
NA.25

양식

powder

포장

pkg of 1 × 1 mg (860636P-1mg)

제조업체/상표

Avanti Research™ - A Croda Brand

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCC([2H])(C([2H])([2H])[2H])[2H])(O)[C@](N)([H])CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O

InChI

1S/C24H47NO7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(27)18(25)17-31-24-23(30)22(29)21(28)20(16-26)32-24/h14-15,18-24,26-30H,2-13,16-17,25H2,1H3/b15-14+/t18-,19+,20+,21+,22-,23+,24+/m0/s1/i1D3,2D2

InChI key

HHJTWTPUPVQKNA-JCMYXXMQSA-N

애플리케이션

Glucosyl(β) Sphingosine-d5 has been used as an internal standard for the quantification of lysohexosylceramide in various samples by liquid chromatography-tandem mass spectrometry.

생화학적/생리학적 작용

Glucosyl sphingosine has an ability to regulate Ca2+ release in the brain microsomes. It acts as a potential biomarker for Gaucher disease (GD).

포장

5 mL Amber Glass Screw Cap Vial (860636P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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설명
가격

Storage Class Code

11 - Combustible Solids

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Glucosylsphingosine is a highly sensitive and specific biomarker for primary diagnostic and follow-up monitoring in Gaucher disease in a non-Jewish, Caucasian cohort of Gaucher disease patients
Rolfs A, et al.
PLoS ONE, 8(11) (2013)
LC-MS/MS multiplex analysis of lysosphingolipids in plasma and amniotic fluid: a novel tool for the screening of sphingolipidoses and Niemann-Pick type C disease
Pettazzoni M, et al.
PLoS ONE, 12(7) (2017)
LC-MS/MS multiplex analysis of lysosphingolipids in plasma and amniotic fluid: a novel tool for the screening of sphingolipidoses and Niemann-Pick type C disease
Pettazzoni M, et al.
Testing, 12(7) (2017)
Mercedes Roca-Espiau et al.
Journal of orthopaedic surgery and research, 14(1), 383-383 (2019-11-23)
Chronic fatigue (CFg) is a prevalent symptom in Gaucher disease (GD) at diagnosis (79%) and remains in a quarter of patients after years of therapy. Bone abnormalities are present in over 70% and peripheral neuropathy in about 11% of the
Magali Pettazzoni et al.
PloS one, 12(7), e0181700-e0181700 (2017-07-28)
The biological diagnosis of sphingolipidoses currently relies on the measurement of specific enzymatic activities and/or genetic studies. Lysosphingolipids have recently emerged as potential biomarkers of sphingolipidoses and Niemann-Pick type C in plasma. We developed a sensitive and specific method enabling
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