추천 제품
분석
>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
양식
powder
포장
pkg of 1 × 1 mg (857230P-1mg)
제조업체/상표
Avanti Research™ - A Croda Brand 857230P
지질 유형
cardiolipins
phospholipids
배송 상태
dry ice
저장 온도
−20°C
SMILES string
O[C@](COP([O-])(O)=O)([H])COCCCCCCCC/C=C\CCCCCCCC.[NH4+]
InChI key
WEOSAIXAEGBVPQ-WBIWQBECSA-N
일반 설명
C18:1 LPA is a bioactive lipid. This lysophosphatidic acid (LPA), soluble lipid is obtained from membrane phospholipid. It is present in blood plasma.
애플리케이션
C18:1 LPA is suitable to stimulate human embryonic kidney 293 cells (HEK 293) cells in luciferase assay. It is also suitable to use as an additive in Dulbecco′s modified eagle medium (DMEM) for transwell migration assay, wound‐healing assay and cell proliferation assay.
생화학적/생리학적 작용
Lysophosphatidic acid (LPA) signaling participates in various cellular processes. It is also associated with neurological disorders, inflammation and cancer.
포장
5 mL Clear Glass Sealed Ampule (857230P-1mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
No data available
Flash Point (°C)
No data available
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이미 열람한 고객
R D Moreno-Fernández et al.
Neuropharmacology, 164, 107896-107896 (2019-12-08)
The LPA1 receptor, one of the six characterized G protein-coupled receptors (LPA1-6) through which lysophosphatidic acid acts, is likely involved in promoting normal emotional behaviours. Current data suggest that the LPA-LPA1-receptor pathway may be involved in mediating the negative consequences
Lysophosphatidic acid and its receptor LPA1 mediate carrageenan induced inflammatory pain in mice
Srikanth M, et al.
European Journal of Pharmacology, 841, 49- 56 (2018)
Autotaxin is a novel target of micro RNA-101-3p
Wang Y, et al.
FEBS Open Bio, 9(4), 707-716 (2019)
Jesica R Williams et al.
The Journal of biological chemistry, 284(25), 17304-17319 (2009-04-16)
Lysophosphatidic acid (LPA) is a ligand for LPA(1-3) of the endothelial differentiation gene family G-protein-coupled receptors, and LPA(4-8) is related to the purinergic family G-protein-coupled receptor. Because the structure-activity relationship (SAR) of GPR92/LPA(5) is limited and whether LPA is its
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