700087P
Avanti
DHEA
Avanti Research™ - A Croda Brand
동의어(들):
DHEA; 3β-hydroxy-5-androsten-17-one; 5-androsten-3β-ol-17-one; dehydroisoandrosterone; trans-dehydroandrosterone; Prasterone
로그인조직 및 계약 가격 보기
모든 사진(2)
About This Item
실험식(Hill 표기법):
C19H28O2
CAS Number:
Molecular Weight:
288.42
MDL number:
UNSPSC 코드:
12352211
NACRES:
NA.25
추천 제품
설명
Dehydroepiandrosterone
분석
>99% (TLC)
양식
powder
포장
pkg of 1 × 1 g (700087P-1g)
제조업체/상표
Avanti Research™ - A Croda Brand
배송 상태
dry ice
저장 온도
−20°C
SMILES string
O[C@H]1CC[C@@]2([C@@H]3[C@H]([C@H]4[C@](CC3)(C(=O)CC4)C)CC=C2C1)C
InChI
1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,13-16,20H,4-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1
InChI key
FMGSKLZLMKYGDP-USOAJAOKSA-N
일반 설명
25-hydroxy-cholesterol is a metabolite of cholesterol. It is produced by macrophages.
DHEA (dehydroepiandrosterone) is an endogenous steroid hormone secreted by the adrenal gland. DHEA serves as precursor to male and female sex hormones (androgens and estrogens).
Dehydroepiandrosterone (DHEA) is a carbon (C)-19 neuroactive steroid. It is synthesized by the adrenal gland in humans and mammals.
생화학적/생리학적 작용
25-hydroxy-cholesterol represses the production of IgA by B cells, manages the migration of activated B cells in the germinal follicle. It regulates the differentiation of monocytes into macrophages. 25-hydroxy-cholesterol plays a critical role in lipid biosynthesis and immunity. It inhibits sterol regulatory element-binding protein (SREBP) proteolytic processing and modulates cholesterol metabolism.
Dehydroepiandrosterone (DHEA) regulates neural functions, such as neurogenesis, neuroprotection, neuronal growth and differentiation. It is used to treat multiple sclerosis. DHEA acts as a precursor of sex steroid biosynthesis.
포장
20 mL Clear Glass Screw Cap Vial (700087P-1g)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
또한 이 제품과 함께 일반적으로 구입
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Repr. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
이미 열람한 고객
Sayali Upasham et al.
The Analyst, 145(3), 784-796 (2019-12-24)
Chronobiology is defined as the temporal fluctuations occurring in the human physiology due to the circadian cycle. These fluctuations are good indicators of the functioning of the Hypothalamic-Pituitary-Adrenal axis (HPA axis) and can be tracked by using biomarkers: cortisol and
25-Hydroxycholesterol: a new life in immunology
McDonald JG and Russell DW
Journal of Leukocyte Biology, 88(6), 1071-1072 (2010)
Sex Hormones in Neurodegenerative Processes and Diseases (2018)
25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages
Shibata N, et al.
The Journal of biological chemistry, 288(50), 35812-35823 (2013)
Joseph S Dillon
Current drug targets. Inflammation and allergy, 4(3), 377-385 (2005-08-17)
Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) are metabolic intermediates in the production of potent androgens, estrogens and other less well-characterized steroids. DHEA(S) and closely related steroid hormones have a variety of immunological effects both in vitro and in vivo in
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