추천 제품
분석
>99% (TLC)
양식
powder
포장
pkg of 1 × 1 g (700001P-1g)
pkg of 1 × 200 mg (700001P-200mg)
pkg of 1 × 25 mg (700001P-25mg)
pkg of 1 × 500 mg (700001P-500mg)
제조업체/상표
Avanti Research™ - A Croda Brand 700001P
응용 분야
vaccine development
배송 상태
dry ice
저장 온도
−20°C
SMILES string
[H][C@](C1)(OC(NCC[N+](C)([H])C)=O)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@@H](C)CCCC(C)C.[Cl-]
InChI
1S/C32H56N2O2.ClH/c1-22(2)9-8-10-23(3)27-13-14-28-26-12-11-24-21-25(36-30(35)33-19-20-34(6)7)15-17-31(24,4)29(26)16-18-32(27,28)5;/h11,22-23,25-29H,8-10,12-21H2,1-7H3,(H,33,35);1H
InChI key
ISXSJGHXHUZXNF-UHFFFAOYSA-N
일반 설명
DC-Cholesterol HCl is a cholesterol derivative and a cationic lipid with a head group and linker moiety.
DC-Cholesterol HCl is a sterol-based transfection reagent.
애플리케이션
DC-Cholesterol HCl is suitable:
- for the preparation of ultrasound cationic microbubbles
- to prepare liposomes
- for the preparation of L-glutathione (GSH), loaded proliposomes
DC-Cholesterol HCl may be used in the preparation of colloidal dispersions for transmission electron microscopy studies. It may also be used in liposome preparation for assessing hexokinase activity, poly (lactic-coglycolicacid) loading and in mRNA transfection studies.
생화학적/생리학적 작용
DC-Cholesterol is an effective transfection agent and a liposome reagent. Liposome of DC-Cholesterol with dioleoylphosphatidylethanolamine (DOPE) are efficient for DNA transfection. It imparts positive surface charge to the microbubbles for ultra sound based transfection of clustered regularly interspaced short palindromic repeats (CRISPRs).
DC-cholesterol is a cationic lipid, known to be the most efficient in gene transfection study.
포장
20 mL Clear Glass Screw Cap Vial (700001P-1g)
20 mL Clear Glass Screw Cap Vial (700001P-500mg)
5 mL Amber Glass Screw Cap Vial (700001P-200mg)
5 mL Amber Glass Screw Cap Vial (700001P-25mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
이미 열람한 고객
C Colonna et al.
International journal of pharmaceutics, 364(1), 108-118 (2008-09-09)
The aim of this work was to investigate lipid-based dried powders as transfection competent carriers capable of promoting the expression of therapeutic genes. The lipid-based vectors were prepared by combining different cationic lipids 1,2-dioleoyl-3-trimethylammoniumpropane chloride (DOTAP), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE), 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)
Modulation of yeast hexokinase on bio-inspired membranes
Umakoshi H and Nishida A
Biochemical Engineering Journal, 69(5), 138-143 (2012)
Cationic cage-like complexes formed by DC-cholesterol, Quil-A, and phospholipid
Lendemans DG, et al.
Journal of Pharmaceutical Sciences, 94(8), 1794-1807 (2005)
ADP-ribosylation reactions, 948-948 (2001)
Pharmaceutical Chemistry ? I, 142-142 (2003)
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