QBD10866

SPDP-dPEG^®₃₆-acid

>95% (HPLC)

• 동의어(들): OPSS-PEG₁₅₀₀-acid, OPSS-PEG₃₆-acid, SPDP-PEG-acid, SPDP-PEG₃₆-COOH, SPDP-PEG₃₆-acid
• 실험식(Hill 표기법): C₈₃H₁₅₈N₂O₃₉S₂
• Molecular Weight: 1872.26
• MDL number: MFCD21363286
• UNSPSC 코드: 12352106
• NACRES: NA.22

속성

• 분석: >95% (HPLC)
• 양식: solid or viscous liquid
• 반응 적합성: reaction type: Pegylations
• 폴리머 구조: shape: linear; functionality: heterobifunctional
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: S(Sc1ncccc1)CCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O
• InChI: 1S/C83H158N2O39S2/c86-81(5-80-125-126-82-3-1-2-6-85-82)84-7-9-90-11-13-92-15-17-94-19-21-96-23-25-98-27-29-100-31-33-102-35-37-104-39-41-106-43-45-108-47-49-110-51-53-112-55-57-114-59-61-116-63-65-118-67-69-120-71-73-122-75-77-124-79-78-123-76-74-121-72-7
• InChI key: YETQZNCXLDFCHR-UHFFFAOYSA-N

설명

특징 및 장점

SPDP-dPEG₃₆-acid is a crosslinking reagent designed to conjugate free amines and sulfhydryls. The single molecular weight (i.e., monodispersed) PEG crossbridge between the two functional groups is 115 atoms (137.8 Å) long. Using a suitable carbodiimide, such as EDC, the propionic acid group reacts with free primary amines to form amide bonds. The pyridyl disulfide (SPDP, also known as OPSS) functional group reacts with free thiols to form disulfide bonds. This product is useful for crosslinking peptides, proteins, and small molecules, and modifying surfaces with suitable reactive sites. SPDP-dPEG₃₆-acid is a monodisperse equivalent of the polymeric PEG₁₅₀₀.

법적 정보

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable