QBD10198

NHS-dPEG^®₁₂-biotin

• 동의어(들): NHS-PEG Linker, Polyethylene glycol
• 실험식(Hill 표기법): C₄₁H₇₂N₄O₁₈S
• Molecular Weight: 941.09
• UNSPSC 코드: 12161502
• PubChem Substance ID: 329823889
• NACRES: NA.22

속성

• 분석: >90%
• 양식: solid or viscous liquid
• 반응 적합성: reagent type: cross-linking reagent; reaction type: Biotinylations; reactivity: amine reactive
• 폴리머 구조: shape: linear; functionality: monofunctional
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC1C2NC(NC2CS1)=O)=O)ON3C(CCC3=O)=O
• InChI: 1S/C41H72N4O18S/c46-36(4-2-1-3-35-40-34(33-64-35)43-41(50)44-40)42-8-10-52-12-14-54-16-18-56-20-22-58-24-26-60-28-30-62-32-31-61-29-27-59-25-23-57-21-19-55-17-15-53-13-11-51-9-7-39(49)63-45-37(47)5-6-38(45)48/h34-35,40H,1-33H2,(H,42,46)(H2,43,44,50)
• InChI key: WOLXSUFTTIRQOU-UHFFFAOYSA-N

설명

특징 및 장점

NHS-dPEG^®₁₂-biotin is used extensively to label molecules that contain a free amine with biotin. The single molecular weight NHS-dPEG^®₁₂-biotin has a long spacer of precise length (47.6 Å) between the biotin moiety and the labeled molecule. This dPEG^® spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG^® spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.

법적 정보

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable