D2388
Dimethyl 3,3′-dithiopropionimidate dihydrochloride
powder
동의어(들):
DTBP, Dimethyl 3,3′-dithio-bis(propionimidate) dihydrochloride, Wang/Richards’ reagent
로그인조직 및 계약 가격 보기
모든 사진(2)
About This Item
실험식(Hill 표기법):
C8H16N2O2S2 · 2HCl
CAS Number:
Molecular Weight:
309.28
MDL number:
UNSPSC 코드:
12352116
PubChem Substance ID:
NACRES:
NA.22
추천 제품
양식
powder
Quality Level
반응 적합성
reagent type: cross-linking reagent
solubility
H2O: 50 mg/mL
저장 온도
2-8°C
SMILES string
Cl.Cl.COC(=N)CCSSCCC(=N)OC
InChI
1S/C8H16N2O2S2.2ClH/c1-11-7(9)3-5-13-14-6-4-8(10)12-2;;/h9-10H,3-6H2,1-2H3;2*1H
InChI key
CQBCVFHLZAVNPF-UHFFFAOYSA-N
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관련 카테고리
애플리케이션
A homobifunctional, cleavable cross-linking reagent. Typically, reacted with primary amines in the pH range 7.0-10.0 to form amidine bonds.
Reactant for:
- Synthesis of glutathione-sensitive cross-linked polyethylenimine gene vector
- Preparation of cyclodextrin-containing polymers designed for gene delivery
- Crosslinking of chick oviduct progesterone-receptor subunits
주의사항
The reagant is readily hydrolyzed at neutral pH. Avoid use of reducing agents during coupling reactions.
기타 정보
Note that the amidine linkage preserves original primary amine positive charge. The disulfide linkage is cleavable by mild reduction. Incorporates an eight atom linker.
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문서
Kanjiro Miyata (The University of Tokyo, Japan) provides insights on the rational design of polymeric materials for “smart” oligonucleotide delivery.
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