940674

DBCO-NHCO-PEG4-amine TFA

≥95%

• 동의어(들): 15-Amino-N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-4,7,10,13-tetraoxapentadecanamide, 4,7,10,13-Tetraoxapentadecanamide, 15-amino-N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl], ADIBO-PEG4-amine TFA
• 실험식(Hill 표기법): C₂₉H₃₇N₃O₆ · xC₂HF₃O₂
• CAS Number: 1255942-08-5
• Molecular Weight: 523.62 (free base basis)
• MDL number: MFCD28334576
• UNSPSC 코드: 12352200

속성

• Quality Level: 100
• 분석: ≥95%
• 양식: solid
• 색상: colorless to yellow-brown
• 저장 온도: −20°C
• SMILES string: O=C(NCCC(=O)N1C=2C=CC=CC2C#CC=3C=CC=CC3C1)CCOCCOCCOCCOCCN
• InChI: 1S/C29H37N3O6.C2HF3O/c30-13-16-36-18-20-38-22-21-37-19-17-35-15-12-28(33)31-14-11-29(34)32-23-26-7-2-1-5-24(26)9-10-25-6-3-4-8-27(25)32;3-2(4,5)1-6/h1-8H,11-23,30H2,(H,31,33);1H
• InChI key: MRRSYYMIRSTYMO-UHFFFAOYSA-N

설명

애플리케이션

DBCO-PEG4-Amine TFA is a heterobifunctional building block with two reactive terminals. The Dibenzocyclooctyne (DBCO) terminus is useful for copper-free click chemistry. DBCO compounds react with azides without need of Cu(I) catalyst due to the strained nature of alkyne resulting in formation of fast and stable triazole linkage. The amine terminus is useful for reaction with carboxylic acid containing linkers in presence in actiavtors such as EDC or HATU.

특징 및 장점

The PEG4 linker is suited for improving solubility of resulting conjugates and provides sufficient length to minimize interactions between macromolecules of interest.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable