934372

MC-Val-Cit-PAB-PNP

≥95%

• 동의어(들): L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N⁵-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-
• 실험식(Hill 표기법): C₃₅H₄₃N₇O₁₁
• CAS Number: 159857-81-5
• Molecular Weight: 737.76
• Beilstein: 10322169
• MDL number: MFCD22200431
• UNSPSC 코드: 12352200
• PubChem Substance ID: 468592337
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: ≥95%
• 양식: powder
• 저장 온도: 2-8°C
• SMILES string: [N+](=O)([O-])c1ccc(cc1)OC(=O)OCc2ccc(cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CCCCCN3C(=O)C=CC3=O)C(C)C)CCCNC(=O)N
• InChI key: HYSPJPGXSALJRR-DHIFEGFHSA-N

설명

애플리케이션

This is a bifunctional cathepsin cleavable linker used in the construction of antibody drug conjugates (ADC).

특징 및 장점

The maleimide functionality can be used for bioconjugation to thiols in monoclonal antibodies while the activated carbonate esters can be used for construction of carbamate linkages with amine containing payloads.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable