907324

Fmoc-L-photo-proline

≥95%

• 동의어(들): (S)-5-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,5-triazaspiro[2.4]hept-1-ene-6-carboxylic acid, (S)-5-Fmoc-1,2,5-triazaspiro[2.4]hept-1-ene-6-carboxylic acid, Diazirine amino acid, Photo-Pro, Photo-crosslinking amino acid, Photoprobe building block
• 실험식(Hill 표기법): C₂₀H₁₇N₃O₄
• CAS Number: 1266778-58-8
• Molecular Weight: 363.37
• MDL number: MFCD31380718
• UNSPSC 코드: 12352209

속성

• 분석: ≥95%
• 양식: powder
• 반응 적합성: reaction type: Fmoc solid-phase peptide synthesis
• mp: 113-116 °C
• 응용 분야: peptide synthesis
• 작용기: Fmoc
• 저장 온도: −20°C

설명

애플리케이션

Fmoc-L-photo-proline is a diazirine-containing, Fmoc-protected proline amino acid and multifunctional probe building blocks. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907286.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

기타 정보

Chemical Probes Unravel an Antimicrobial Defense Response Triggered by Binding of the Human Opioid Dynorphin to a Bacterial Sensor Kinase

Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

안전성 정보

• 픽토그램: GHS02
• 신호어: Danger
• 유해 및 위험 성명서: H242
• 예방조치 성명서: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Hazard Classifications: Self-react. C
• Storage Class Code: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable