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![2-[2-(2-Aminoethoxy)ethoxy]ethanol ≥96.0% (GC)](/deepweb/assets/sigmaaldrich/product/structures/237/185/b94eadd2-5a2c-4a5b-a13d-3d3905df0dbc/640/b94eadd2-5a2c-4a5b-a13d-3d3905df0dbc.png)
Quality Level
분석
95%
양식
solid
mp
184-186 °C (dec.) (lit.)
작용기
carboxylic acid
SMILES string
OC(=O)C1CNC(=O)N1
InChI
1S/C4H6N2O3/c7-3(8)2-1-5-4(9)6-2/h2H,1H2,(H,7,8)(H2,5,6,9)
InChI key
KZKRPYCBSZIQKN-UHFFFAOYSA-N
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애플리케이션
Reactant for synthesis of human BACE-1 inhibitors
Additive for crystal nucleation and growth
Additive for crystal nucleation and growth
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Heuisul Park et al.
Bioorganic & medicinal chemistry letters, 18(9), 2900-2904 (2008-04-25)
We describe synthesis and evaluation of a series of cyclic urea derivatives with hydroxylethylamine isostere. Modification of P3, P1, and P2' and combination of SAR display a >100-fold increase in potency with good cellular activity (IC(50)=0.15microM) relative to the previously
S Samuels et al.
Pharmacology, biochemistry, and behavior, 24(1), 143-146 (1986-01-01)
DBA/2J mice were exposed in utero, between days 15-18 of gestation, to either of two enzyme inhibitors, previously shown to decrease blood-brain, large-neutral amino acid transport in adults: L-methionine-RS-sulfoximine and 2-imidazolidone-4-carboxylic acid. The young mice demonstrated persistently altered motor behavior
S. Devarakonda, et al.,
Journal of Crystal Growth, 204, 525-538 (1999)
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