764221

Propargyl-N-hydroxysuccinimidyl ester

• 동의어(들): 2,5-Dioxopyrrolidin-1-yl 3-(prop-2-ynyloxy)propanoate, 3-(2-Propyn-1-yloxy)propanoic acid 2,5-dioxo-1-pyrrolidinyl ester, Alkyne-NHS ester, Propargyl-succinimidyl-ester
• 실험식(Hill 표기법): C₁₀H₁₁NO₅
• CAS Number: 1174157-65-3
• Molecular Weight: 225.20
• MDL number: MFCD13184973
• UNSPSC 코드: 12352108
• PubChem Substance ID: 329767108
• NACRES: NA.22

속성

• 양식: solid
• Quality Level: 100
• 반응 적합성: reaction type: click chemistry; reagent type: cross-linking reagent
• mp: 36-41 °C
• 작용기: NHS ester; alkyne
• 저장 온도: −20°C
• SMILES string: C#CCOCCC(ON1C(CCC1=O)=O)=O
• InChI: 1S/C10H11NO5/c1-2-6-15-7-5-10(14)16-11-8(12)3-4-9(11)13/h1H,3-7H2
• InChI key: WKIKHHMUNOVQLD-UHFFFAOYSA-N

설명

애플리케이션

Propargyl-N-hydroxysuccinimidyl ester may be used as a tool for identifying nucleophilic ligandable hotspots by chemoproteomic approaches.

Propargyl-NHS ester is an amine reactive reagent for derivatizing peptides, antibodies, amine coated surfaces etc, with a terminal alkyne. The alkyne can be reacted with an azide containing compound or biomolecule via copper catalyzed azide-alkyne click chemistry to yield a stable triazole linkage.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable