추천 제품
Grade
anhydrous
Quality Level
분석
98%
광학 활성
[α]20/D −118°, c = 2.5 in chloroform
mp
175-178 °C (dec.) (lit.)
작용기
ether
SMILES string
[H][C@@]12CC(=O)N3c4cc(OC)c(OC)cc4[C@]56CC[N@H]7CC(=CCO1)[C@]([H])(C[C@@H]57)[C@]2([H])[C@]36[H]
InChI
1S/C23H26N2O4/c1-27-16-8-14-15(9-17(16)28-2)25-20(26)10-18-21-13-7-19-23(14,22(21)25)4-5-24(19)11-12(13)3-6-29-18/h3,8-9,13,18-19,21-22H,4-7,10-11H2,1-2H3/t13-,18-,19-,21-,22-,23+/m0/s1
InChI key
RRKTZKIUPZVBMF-IBTVXLQLSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Brucine is the major active pharmacological component of Strychnos nux-vomica seeds, which is known for its anti-inflammatory and analgesic activities.
애플리케이션
Brucine may be used as chiral resolving agent for the optical resolution of tertiary acetylenic alcohols into enantiomers.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 1 Oral - Acute Tox. 2 Inhalation - Aquatic Chronic 3
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
이미 열람한 고객
A Novel Brucine Gel Transdermal Delivery System Designed for Anti-Inflammatory and Analgesic Activities.
Wu P, et al.
International Journal of Molecular Medicine, 18(4), 757-757 (2017)
Jun Chen et al.
Fitoterapia, 82(8), 1302-1308 (2011-10-01)
The toxicity depending on both dose and administration route is the major obstacle to the development of brucine, a bioactive alkaloid from Semen Strychni. In this study, the apparent partition coefficient and plasma protein binding extent of brucine were determined.
Mohsen Behpour et al.
Phytochemical analysis : PCA, 23(2), 95-102 (2011-05-28)
Strychnos nux-vomica L. (Loganiaceae), widely used in folk medicine, is grown extensively in southern Asian countries. Its major bioactive constituents are strychnine and brucine, which are frequently used in traditional herbal medicines for treatment of nervous diseases, vomiting and traumatic
S S Agrawal et al.
Life sciences, 89(5-6), 147-158 (2011-06-21)
Brucine (BRU), a natural plant alkaloid is reported to possess cytotoxic and antiproliferative activities. In this study we aimed to investigate its in vitro and in vivo antitumor and antiangiogenic effects. Cell proliferation and viability was assessed using microculture tetrazolium
Hong-Mei Zhang et al.
Molecular biology reports, 39(4), 4937-4947 (2011-12-14)
The features of brucine (BC) binding to two blood proteins, bovine hemoglobin (BHb), and bovine serum albumin (BSA), were investigated via fluorescence, circular dichroism and UV/Vis absorption spectroscopy. The results revealed that BC caused the fluorescence quenching of blood proteins
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