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Merck
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주요 문서

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379115

Sigma-Aldrich

DCC

1.0 M in methylene chloride, for peptide synthesis

동의어(들):

N,N′-Dicyclohexylcarbodiimide solution

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모든 사진(1)

About This Item

Linear Formula:
C6H11N=C=NC6H11
CAS Number:
538-75-0
Molecular Weight:
206.33
MDL number:
MFCD00011659
UNSPSC 코드:
12352111
PubChem Substance ID:
24863614
NACRES:
NA.22

제품명

DCC, 1.0 M in methylene chloride

양식

liquid

Quality Level

200

반응 적합성

reaction type: Coupling Reactions

농도

1.0 M in methylene chloride

density

1.247 g/mL at 25 °C

응용 분야

peptide synthesis

SMILES string

C1CCC(CC1)N=C=NC2CCCCC2

InChI

1S/C13H22N2/c1-3-7-12(8-4-1)14-11-15-13-9-5-2-6-10-13/h12-13H,1-10H2

InChI key

QOSSAOTZNIDXMA-UHFFFAOYSA-N

유전자 정보

human ... EPHX2(2053)
mouse ... Ephx2(13850)

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관련 카테고리

애플리케이션

DCC (N,N′-Dicyclohexylcarbodiimide) is mainly used to mediate peptide coupling and also to activate carboxylic acids for esterification.

픽토그램

Health hazardCorrosionExclamation mark
GHS08,GHS05,GHS07

신호어

Danger

유해 및 위험 성명서

H312,H315,H317,H318,H336,H351

Hazard Classifications

Acute Tox. 4 Dermal - Carc. 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

표적 기관

Central nervous system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

개인 보호 장비

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
MKCQ3725
MKCN6433
MKCM2709
MKCL3517
MKCJ0017

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Effects of amounts of additives on peptide coupling mediated by a water?soluble carbodiimide in alcohols.
Nozaki S.
The Journal of Peptide Research, 54(2), 162-167 (1999)
Liposomes containing alkylated methotrexate analogues for phospholipase A 2 mediated tumor targeted drug delivery.
Kaasgaard T, et al.
Chemistry and Physics of Lipids, 157(2), 94-103 (2009)
Denys Pogoryelov et al.
Nature chemical biology, 6(12), 891-899 (2010-10-26)
The microscopic mechanism of coupled c-ring rotation and ion translocation in F(1)F(o)-ATP synthases is unknown. Here we present conclusive evidence supporting the notion that the ability of c-rings to rotate within the F(o) complex derives from the interplay between the
Masashi Toei et al.
The Journal of biological chemistry, 288(36), 25717-25726 (2013-07-31)
N,N-Dicyclohexylcarbodiimide (DCCD) is a classical inhibitor of the F0F1-ATP synthase (F0F1), which covalently binds to the highly conserved carboxylic acid of the proteolipid subunit (c subunit) in F0. Although it is well known that DCCD modification of the c subunit
Kenji Mizutani et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(33), 13474-13479 (2011-08-05)
The prokaryotic V-ATPase of Enterococcus hirae, closely related to the eukaryotic enzymes, provides a unique opportunity to study the ion-translocation mechanism because it transports Na(+), which can be detected by radioisotope (22Na(+)) experiments and X-ray crystallography. In this study, we
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문서

Carbodiimide-mediated peptide coupling

Carbodiimide-mediated peptide coupling remains to the most frequently used technique.

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