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Merck
모든 사진(2)

주요 문서

288225

Sigma-Aldrich

Chloro(triethylphosphine)gold(I)

97%

동의어(들):

(Triethylphosphine)gold(I) chloride

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About This Item

Linear Formula:
(C2H5)3PAuCl
CAS Number:
Molecular Weight:
350.58
EC Number:
MDL number:
UNSPSC 코드:
12161600
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

97%

양식

solid

반응 적합성

core: gold
reagent type: catalyst

bp

210 °C/0.03 mmHg (lit.)

mp

84-86 °C (lit.)

SMILES string

Cl[Au].CCP(CC)CC

InChI

1S/C6H15P.Au.ClH/c1-4-7(5-2)6-3;;/h4-6H2,1-3H3;;1H/q;+1;/p-1

InChI key

SYBBXLKWGHAVHP-UHFFFAOYSA-M

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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시험 성적서(COA)

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문서 라이브러리 방문

F Märki et al.
Arzneimittel-Forschung, 42(3), 328-333 (1992-03-01)
The effect of several gold complexes on the activity of phospholipase C from human blood platelets was studied in vitro. Aurothiomalate and auranofin--2 agents used for the chrysotherapy of rheumatoid arthritis--, gold chloride, (triethylphosphine)gold chloride, and 5 newly synthesized (triethylphosphine)gold
31P nuclear-magnetic-resonance studies at 24 and 162 MHz of blood containing an anti-arthritic gold phosphine: relaxation via chemical-shift anisotropy.
N A Malik et al.
Biochemical Society transactions, 8(5), 635-636 (1980-10-01)
R M Snyder et al.
Biochemical pharmacology, 36(5), 647-654 (1987-03-01)
Auranofin (AF) is an orally active chrysotherapeutic agent whose precise mechanism of action with its putative target cell, the macrophage, is not known. In a previous paper, we described a sequential thiol exchange mechanism that explained auranofin's molecular mechanism of
N A Malik et al.
Journal of inorganic biochemistry, 12(4), 317-322 (1980-07-01)
Contrasting reactions of the antiarthritic complexes ClAuPEt3 and ClAu(PEt3)2 with blood have been studied by 31P nmr spectroscopy. The monophosphine complex has two binding sites in erythrocytes, probably at the SH groups of glutathione and haemoglobin. The bis complex solidifies
Cellular and molecular pharmacology of auranofin and related gold complexes.
S T Crooke et al.
Biochemical pharmacology, 35(20), 3423-3431 (1986-10-15)

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