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Merck
모든 사진(1)

주요 문서

126462

Sigma-Aldrich

6,7-Dimethyl-2,3-di(2-pyridyl)quinoxaline

98%

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About This Item

실험식(Hill 표기법):
C20H16N4
CAS Number:
Molecular Weight:
312.37
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

98%

양식

powder

mp

191-193 °C (lit.)

SMILES string

Cc1cc2nc(-c3ccccn3)c(nc2cc1C)-c4ccccn4

InChI

1S/C20H16N4/c1-13-11-17-18(12-14(13)2)24-20(16-8-4-6-10-22-16)19(23-17)15-7-3-5-9-21-15/h3-12H,1-2H3

InChI key

NACXMBPTPBZQHY-UHFFFAOYSA-N

애플리케이션

6,7-Dimethyl-2,3-di-(2-pyridyl)quinoxaline has been used as an internal standard to investigate the clinical pharmacokinetics of nelfinavir mesylate, a potent inhibitor of HIV-1 protease.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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시험 성적서(COA)

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문서 라이브러리 방문

E Y Wu et al.
Journal of chromatography. B, Biomedical sciences and applications, 695(2), 373-380 (1997-08-01)
Nelfinavir mesylate, a potent and orally bioavailable inhibitor of HIV-1 protease (Ki=2 nM), has undergone Phase III clinical evaluation in a large population of HIV-positive patients. A high-performance liquid chromatography analytical method was developed to determine the pharmacokinetic parameters of
B Louveau et al.
Biomedical chromatography : BMC, 30(12), 2009-2015 (2016-06-10)
A precise and accurate high-performance liquid chromatography (HPLC) quantification method of rifampicin in human plasma was developed and validated using ultraviolet detection after an automatized solid-phase extraction. The method was validated with respect to selectivity, extraction recovery, linearity, intra- and
Sara Baldelli et al.
Therapeutic drug monitoring, 36(6), 739-745 (2014-04-18)
Recently, the European Medicines Agency (EMA) has released new guidelines on the validation of bioanalytical methods. In this work, we compared the analytical performance of 2 high-performance liquid chromatography with tandem mass spectrometry methods designed for the quantification of the

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