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Merck

MAP2K1

mitogen-activated protein kinase kinase 1

동의어:
CFC3, MAPKK1, MEK1, MKK1, PRKMK1
:
UniProtKB ID:
Clone ID:
  • Human(5604) Summary: The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]
  • Mouse(26395) mitogen-activated protein kinase kinase 1
  • Rat(170851) mitogen activated protein kinase kinase 1
  • Zebrafish(406728) mitogen-activated protein kinase kinase 1
  • chicken(415549) mitogen-activated protein kinase kinase 1
  • dog(478347) mitogen-activated protein kinase kinase 1
  • Horse(100065996) mitogen-activated protein kinase kinase 1
  • cow(533199) mitogen-activated protein kinase kinase 1
  • domestic cat(101081387) mitogen-activated protein kinase kinase 1
  • sheep(101123635) mitogen-activated protein kinase kinase 1
  • naked mole-rat(101715628) mitogen-activated protein kinase kinase 1
  • Domestic Rabbit(100009316) mitogen-activated protein kinase kinase 1
  • domestic guinea pig(100712888) mitogen-activated protein kinase kinase 1

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ELISA

Product Number
설명
Phosphotyrosine MAP2K1 ELISA Kit, ,
human

Antibodies

Product Number
설명
종별 반응성
응용분야
Anti-phospho-MAP2K1 (pThr386) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
western blot
Anti-phospho-MAP2K1 (pThr291) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
western blot
Anti-MAP2K1 (Ab-221) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse
응용분야
immunohistochemistry
western blot
Anti-MEK1 Antibody, Upstate®, from rabbit,
종별 반응성
human, mouse, rat
응용분야
immunoprecipitation (IP)
western blot
Anti-MEK1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
설명
U0126 ethanolate, ≥98% (HPLC), powder,
human
PD184352, ≥98% (HPLC),
human
PD 98,059, solid,
human

Proteins

Product Number
설명
MEK1 Protein, inactive, 50 g, Unactive, N-terminal GST & C-terminal His6-tagged, recombinant full-length human MEK1, for use in Kinase Assays.,
human
MEK1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
mouse

esiRNA

Product Number
설명
MISSION® esiRNA, targeting mouse Map2k1,
mouse
MISSION® esiRNA, targeting human MAP2K1,
human