SAB5703036

Anti-Phospho-BTK(pTyr223) Antibody, clone 10F4W10, Rabbit Monoclonal

• Synonym(s): AGMX1, AT, ATK, BPK, IMD1, PSCTK1, XLA
• UNSPSC Code: 12352203
• NACRES: NA.46

Properties

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 10F4W10, monoclonal
• form: liquid
• species reactivity: rat, human, rat
• concentration: 0.3 mg/mL
• technique(s): western blot: 1:500 - 1:2000
• color: colorless
• isotype: IgG
• immunogen sequence: ALYDY
• UniProt accession no.: Q06187
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... BTK(695)

Description

General description

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]

Immunogen

A synthetic phosphorylated peptide around Y223 of human BTK (Q06187).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1