52194

Tetramethylrhodamine isothiocyanate–Dextran

average mol wt 500,000

• Synonym(s): TRITC Dextran, TRITC-Dextran 500, TRITC-Dextran
• MDL number: MFCD00132418
• UNSPSC Code: 12352116
• NACRES: NA.32

Properties

• biological source: synthetic
• Quality Level: 100
• form: powder or crystals
• mol wt: average mol wt 500,000
• extent of labeling: 0.001-0.008 mol/mol TRITC glucose
• fluorescence: λ_ex 550 nm; λ_em 575 nm±5 nm in 0.1 M Tris pH 8.0
• application(s): cell analysis

Description

General description

Tetramethylrhodamine isothiocyanate–Dextran, also known as TRITC-Dextran or TRITC-Dextran 500, is a fluorescent dye and a novel drug. The fluorescent activity of TRITC-Dextran is detected at 555nm wavelength. The TRITC-Dextran molecules are released in the cells through passive diffusion due to a concentration gradient.

Application

Tetramethylrhodamine isothiocyanate–Dextran (TRITC-Dextran 500) is use as a fluorescent probe to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular delivery.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302 + H312 + H332,H315,H319,H335
• Precautionary Statements: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable