45698

Trichlorfon

PESTANAL^®, analytical standard

• Synonym(s): (2,2,2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester, Metrifonate
• Empirical Formula (Hill Notation): C₄H₈Cl₃O₄P
• CAS Number: 52-68-6
• Molecular Weight: 257.44
• Beilstein: 1709434
• EC Number: 200-149-3
• MDL number: MFCD00055272
• UNSPSC Code: 41116107
• PubChem Substance ID: 329756910
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• product line: PESTANAL^®
• shelf life: limited shelf life, expiry date on the label
• application(s): agriculture; environmental
• format: neat
• storage temp.: 2-8°C
• SMILES string: COP(=O)(OC)C(O)C(Cl)(Cl)Cl
• InChI: 1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3
• InChI key: NFACJZMKEDPNKN-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Trichlorfon also known as metrifonate, is an insecticide that functions as an inhibitor of acetylcholine esterase. Trichlorfon has been shown to induce DNA damage and genetic defects in numerous cell lines in addition to inducing aneuploidy in male mouse germ cells.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS08,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H302 + H312,H317,H334,H410
• Precautionary Statements: P261 - P264 - P273 - P280 - P301 + P312 - P302 + P352 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Resp. Sens. 1 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves