763918

DL-α-Tocopherol methoxypolyethylene glycol succinate solution

5 wt. % in H₂O

• Synonym(s): Polyethylene glycol, TPGS-750-M
• Linear Formula: (C₂H₄O)_nC₃₄H₅₆O₅
• CAS Number: 1309573-60-1
• MDL number: MFCD12546177
• UNSPSC Code: 51171641
• NACRES: NA.22

Properties

• form: liquid
• Quality Level: 100
• reaction suitability: reagent type: catalyst; reaction type: C-H Activation; reagent type: surfactant
• IVD: for in vitro diagnostic use
• greener alternative product characteristics: Catalysis; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• concentration: 5 wt. % in H₂O
• refractive index: n20/D 1.340
• density: 0.981 g/mL at 25 °C
• greener alternative category: Aligned,

Description

General description

Learn More at the Professor and Product Portal of Professor Bruce Lipshutz.

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product TPGS-750-M is a lead surfactant for many transition metal-catalyzed cross-couplings and has been enhanced for catalytic efficiency. Find details here.

Application

On the Way Towards Greener Transition-Metal-Catalyzed Processes as Quantified by E Factors

Nonionic amphile used to increase aqueous solubility of lipophilic catalysts and substrates. Olefin metathesis, Sonogashira, Suzuki-Miyaura, and Buchwald cross-coupling reactions have been successfully performed in aqueous media employing TPGS-750-M.

Second generation amphiphile which forms micelles upon dissolution in water allowing a variety of cross-coupling reactions to take place in water instead of organic solvent.

Included among the possible reactions are:

• Olefin metathesis
• Pd-catalyzed cross coupling reactions including Heck, Suzuki-Miyaura, Sonogashira and Buchwald-Hartwig reactions
• C-H activation reactions

Second generation amphiphile for cross-coupling reactions in water

Other Notes

Watch Professor Lipshutz talk about TPGS-750-M in this webinar:
From milligrams to kilograms: synthetic chemistry following nature′s lead

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable