1316004

Hydrocortisone

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione, 17-Hydroxycorticosterone, 4-Pregnene-11β,17α,21-triol-3,20-dione, Cortisol, Kendall’s compound F, Reichstein’s substance M
• Formula empirica (notazione di Hill): C₂₁H₃₀O₅
• CAS Number: 50-23-7
• Peso molecolare: 362.46
• Beilstein: 1354819
• Numero MDL: MFCD00011654
• Codice UNSPSC: 41116107
• ID PubChem: 329750063
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: hydrocortisone
• Produttore/marchio commerciale: USP
• Punto di fusione: 211-214 °C (lit.)
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Stringa SMILE: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO
• InChI: 1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1; JYGXADMDTFJGBT-VWUMJDOOSA-N
• Informazioni sul gene: human ... NR3C1(2908)

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Hydrocortisone USP reference standard suitable for use in specified USP compendial quality tests and assays.

Also used to prepare standard stock, standard, and system suitability solution for assay, identification, and performance test by liquid chromatography in accordance with the given below monographs of United States Pharmacopeia (USP) :

• Hydrocortisone Sodium Succinate for Injection
• Hydrocortisone Tablets
• Hydrocortisone Gel
• Hydrocortisone Lotion

Azioni biochim/fisiol

Primary glucocorticoid secreted by the adrenal cortex.

Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na²⁺ retention potency.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H360Df,H373
• Consigli di prudenza: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Classi di pericolo: Repr. 1A - STOT RE 2
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable