S5261

Sodium selenite

BioReagent, suitable for cell culture, ≥98%

• Sinonimo/i: Selenious acid, Sodium salt
• Formula condensata: Na₂SeO₃
• CAS Number: 10102-18-8
• Peso molecolare: 172.94
• Numero CE: 233-267-9
• Numero MDL: MFCD00003489
• Codice UNSPSC: 12352205
• ID PubChem: 24899643
• NACRES: NA.75

Proprietà

• Origine biologica: synthetic (inorganic)
• Livello qualitativo: 200
• Nome Commerciale: BioReagent
• Saggio: ≥98%
• Stato: powder
• tecniche: cell culture | mammalian: suitable
• Punto di fusione: >350 °C (lit.)
• Solubilità: water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
• Stringa SMILE: [Na+].[Na+].[O-][Se]([O-])=O
• InChI: 1S/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2; BVTBRVFYZUCAKH-UHFFFAOYSA-L

Descrizione

Applicazioni

Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.

This product is cell culture tested (0.005 mg/L) and is appropriate for use in cell culture applications.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS09
• Avvertenze: Danger
• Indicazioni di pericolo: H300 + H330,H315,H317,H319,H411
• Consigli di prudenza: P260 - P273 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
• Rischi supp: EUH031
• Codice della classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges