P4562

Sodium pyruvate

powder, BioXtra, suitable for mouse embryo cell culture

• Sinonimo/i: α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt, Pyruvic acid sodium salt
• Formula condensata: CH₃COCOONa
• CAS Number: 113-24-6
• Peso molecolare: 110.04
• Beilstein: 3568341
• Numero CE: 204-024-4
• Numero MDL: MFCD00002586
• Codice UNSPSC: 12352207
• ID PubChem: 24898552
• NACRES: NA.75

Proprietà

• Nome Commerciale: BioXtra
• Livello qualitativo: 200
• Saggio: ≥99%
• Stato: powder
• tecniche: cell culture | embryo: suitable
• Punto di fusione: >300 °C (lit.)
• Solubilità: H₂O: 100 mg/mL
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: [Na+].CC(=O)C([O-])=O
• InChI: 1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1; DAEPDZWVDSPTHF-UHFFFAOYSA-M

Descrizione

Descrizione generale

Pyruvate, the end-product of the glycolysis pathway, is the anion of pyruvic acid.

Applicazioni

Sodium pyruvate has been used:

• as a supplement in Ca²⁺ + N-Tris(hydroxymethil)methyl-2-aminoethanesulfonic acid (TES)–NaCl medium for sperm incubation
• as a supplement in TCM-199 hepes modification solution for cumulus-oocytes complexes (COC′s) culture
• as a supplement in Dulbecco′s modified Eagle medium (DMEM) to culture mouse primary hepatocytes (MPHs) and also to intraperitoneally inject fasted mice for glucose production assessment

Azioni biochim/fisiol

Sodium pyruvate is mainly used as a constituent in culture broth and media. It exhibits anti-oxidation and anti-inflammatory properties. Hence sodium pyruvate is considered a possible therapy for allergic rhinitis. Sodium pyruvate might also be a new approach treating lactic acidosis.

Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. Sodium pyruvate attenuates oxidative stress in vitro. The 100 mM solution should be diluted at 1:100 for most cell culture applications. This product has been qualified for use in mouse embryo cultures.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H317,H319
• Consigli di prudenza: P280 - P302 + P352 - P305 + P351 + P338
• Classi di pericolo: Eye Irrit. 2 - Skin Sens. 1B
• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)