BP576

Hydrocortisone

British Pharmacopoeia (BP) Assay Standard

• Sinonimo/i: 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione, 17-Hydroxycorticosterone, 4-Pregnene-11β,17α,21-triol-3,20-dione, Cortisol, Kendall’s compound F, Reichstein’s substance M
• Formula empirica (notazione di Hill): C₂₁H₃₀O₅
• CAS Number: 50-23-7
• Peso molecolare: 362.46
• Beilstein: 1354819
• Numero MDL: MFCD00011654
• Codice UNSPSC: 41116107
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: hydrocortisone
• Stato: solid
• Durata: limited shelf life, expiry date on the label
• Produttore/marchio commerciale: BP
• Punto di fusione: 211-214 °C (lit.)
• applicazioni: pharmaceutical; pharmaceutical small molecule
• Formato: neat
• Stringa SMILE: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO
• InChI: 1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1; JYGXADMDTFJGBT-VWUMJDOOSA-N
• Informazioni sul gene: human ... NR3C1(2908)

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Hydrocortisone BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Tretinoin, Hydrocortisone and Hydroquinone Cream

Miconazole and Hydrocortisone Acetate Cream

Hydrocortisone Sodium Succinate Injection

Prednisolone Tablets

Miconazole and Hydrocortisone Cream

Miconazole and Hydrocortisone Ointment

Hydrocortisone and Neomycin Cream

Hydrocortisone and Clioquinol Ointment

Hydrocortisone Sodium Phosphate Oral Solution

Prednisolone Gastro-resistant Tablets

Hydrocortisone Sodium Phosphate

Hydrocortisone Sodium Phosphate Injection

Hydrocortisone and Clioquinol Cream

Methylprednisolone Tablets

Hydrocortisone Acetate Oral Suspension

Hydrocortisone Cream

Hydrocortisone Oromucosal Tablets

Azioni biochim/fisiol

Primary glucocorticoid secreted by the adrenal cortex.

Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na²⁺ retention potency.

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H360Df,H373
• Consigli di prudenza: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Classi di pericolo: Repr. 1A - STOT RE 2
• Organi bersaglio: Adrenal gland,Bone marrow
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable