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Merck

33120-M

Sigma-Aldrich

N,N-Dimethylformamide

puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99.8% (GC)

Synonym(s):

DMF, NSC 5356

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About This Item

Linear Formula:
HCON(CH3)2
CAS Number:
Molecular Weight:
73.09
Beilstein:
605365
EC Number:
MDL number:
UNSPSC Code:
12352111
PubChem Substance ID:
NACRES:
NA.21
Assay:
≥99.8% (GC)
Technique(s):
cell culture | plant: suitable
Bp:
152-154 °C
153 °C (lit.)
Vapor pressure:
2.7 mmHg ( 20 °C)
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grade

ACS reagent
puriss. p.a.

Quality Level

Agency

reag. Ph. Eur.

vapor density

2.5 (vs air)

vapor pressure

2.7 mmHg ( 20 °C)

Assay

≥99.8% (GC)

form

liquid

autoignition temp.

833 °F

expl. lim.

15.2 %

technique(s)

cell culture | plant: suitable

impurities

≤0.001% non-volatile matter
≤0.003% free acid (as CH3COOH)
≤0.005% free alkali (as NH3)
≤0.1% water (Karl Fischer)

color

APHA: ≤15

refractive index

n20/D 1.4290-1.4310
n20/D 1.430 (lit.)

pH

6.7

bp

152-154 °C
153 °C (lit.)

mp

−61 °C (lit.)

density

0.948-0.950 g/mL at 20 °C
0.944 g/mL (lit.)

cation traces

Al: ≤0.5 mg/kg
B: ≤0.02 mg/kg
Ba: ≤0.1 mg/kg
Bi: ≤0.1 mg/kg
Ca: ≤0.5 mg/kg
Cd: ≤0.05 mg/kg
Co: ≤0.02 mg/kg
Cr: ≤0.02 mg/kg
Cu: ≤0.02 mg/kg
Fe: ≤0.1 mg/kg
K: ≤0.5 mg/kg
Li: ≥0.1 mg/kg
Mg: ≤0.1 mg/kg
Mn: ≤0.02 mg/kg
Mo: ≤0.1 mg/kg
Na: ≤1 mg/kg
Ni: ≤0.02 mg/kg
Pb: ≤0.1 mg/kg
Sn: ≤0.1 mg/kg
Sr: ≤0.1 mg/kg
Zn: ≤0.1 mg/kg

SMILES string

[H]C(=O)N(C)C

InChI

1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3

InChI key

ZMXDDKWLCZADIW-UHFFFAOYSA-N

General description

N,N-Dimethylformamide (DMF) is commonly employed as a solvent for various organic reactions. DMF is a useful solvent employed for the isolation of chlorophyll from plant tissues. It is widely employed reagent in organic synthesis. It plays multiple roles in various reactions such as solvent, dehydrating agent, reducing agent as well as catalyst. It is a multipurpose building block for the synthesis of compounds containing O, -CO, -NMe2, -CONMe2, -Me, -CHO as functional groups.

Application

N,N-Dimethylformamide (DMF) may be employed as a solvent in the following studies:
  • Extraction of chlorophyll containing pigments from the intact tissues of cotyledons of Cucumis sativus.
  • Isolation of chlorophyll a from the cell cultures of unicellular marine algae.4
  • As reducing agent and solvent for the preparation of Au@Ag core-shell nanocrystals.
Solvent for many hydrophobic organic compounds.

Packaging

2.5 L also available in PE-bottles


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Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

136.4 °F - closed cup

Flash Point(C)

58 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH SVHC Candidate List

CAS No.

EU REACH Annex XVII (Restriction List)

CAS No.


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