901243

4-(Acetylamino)phenyl]imidodisulfuryl difluoride

≥98%

• Synonym(s): (4-Acetamidophenyl)(fluorosulfonyl)sulfamoyl fluoride, AISF
• Empirical Formula (Hill Notation): C₈H₈F₂N₂O₅S₂
• CAS Number: 2172794-56-6
• Molecular Weight: 314.29
• MDL number: MFCD31625434
• UNSPSC Code: 12352101
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥98%
• form: powder or crystals
• mp: 146-149 °C
• functional group: amide
• SMILES string: F[S](=O)(=O)N([S](=O)(=O)F)c1ccc(cc1)NC(=O)C
• InChI key: SMMIWAIOWMUFCR-UHFFFAOYSA-N

Description

Application

4-(Acetylamino)phenyl]imidodisulfuryl difluoride (AISF) is a shelf-stable, crystalline reagent for synthesis of fluorosulfates and sulfamoyl fluorides via reaction with phenol and amine nucleophiles. A convenient alternative to the toxic sulfuryl fluoride gas traditionally required for installation of the valuable -SO₂F functional group, the solid reagent AISF will find wide utility in preparation of synthetic precursors as well as chemical biology, polymer chemistry, cross-coupling, and deoxyfluorination applications.

Other Notes

Introduction of a Crystalline, Shelf-Stable Reagent for the Synthesis of Sulfur(VI) Fluorides

Technology Spotlight

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable