G6392

L-Glutamine

γ-irradiated, BioXtra, suitable for cell culture

• Szinonimák: (S)-2,5-Diamino-5-oxopentanoic acid, L-Glutamic acid 5-amide, Levoglutamide
• Lineáris képlet: H₂NCOCH₂CH₂CH(NH₂)CO₂H
• CAS Number: 56-85-9
• Molekulatömeg: 146.14
• Beilstein: 1723797
• EC-szám: 200-292-1
• MDL-szám: MFCD00008044
• UNSPSC kód: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24895254
• NACRES: NA.75

Tulajdonságok

• Minőségi szint: 200
• sterilitás: γ-irradiated
• termékcsalád: BioXtra
• Forma: powder
• kiszerelés: vial of 0.292 g
• technika/technikák: cell culture | mammalian: suitable
• szennyeződések: endotoxin, tested
• szín: white to faint yellow
• mp: 185 °C (dec.) (lit.)
• oldhatóság: H₂O: 10 mL/vial, clear to slightly hazy
• SMILES string: N[C@@H](CCC(N)=O)C(O)=O
• InChI: 1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
• Nemzetközi kémiai azonosító kulcs: ZDXPYRJPNDTMRX-VKHMYHEASA-N
• Géninformáció: rat ... Ggt1(116568)

Leírás

Alkalmazás

L-Glutamine has been used as a media supplement:

• for cochlear organotypic culturing
• in Iscove′s modified Dulbecco′s medium for HeLa cells culturing
• in Dulbecco′s modified Eagle′s medium for primary hepatocyte cell culturing

Biokémiai/fiziológiai hatások

L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

Glutamine mediates protein turnover via cellular mTOR (mammalian target of rapamycin) signalling. It is also known to be associated with the inhibition of apoptosis.

L-glutamine is an essential amino acid that is a crucial component of culture media, and serves as a major energy source for cells in culture. Optimal cell performance usually requires supplementation of the medium with L-glutamine prior to use.

Kiszerelés

50 mL amber serum vial with rubber stopper.

Alkalmasság

Qualified for use in cell culture applications, especially serum-free cell culture.

Feloldás

Prepares a 200 mM solution when reconstituted to 10 mL with sterile water.

Egyéb megjegyzések

The dipeptide L-Ala-LGln is frequently used in modern serum-free media formulations because it provides a more stable form of glutamine in vitro.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, type N95 (US)