5341

Progesterone

Steroid hormone secreted by the corpus luteum during the latter half of the menstrual cycle.

• Synonym(s): Progesterone, Δ⁴-Pregnene-3,20-dione
• Empirical Formula (Hill Notation): C₂₁H₃₀O₂
• CAS Number: 57-83-0
• Molecular Weight: 314.46
• MDL number: MFCD00003658
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• description: RTECS - TW0175000; Merck USA index - 14, 7773
• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: crystalline solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• solubility: ethanol: 10 mg/mL
• shipped in: ambient
• storage temp.: 10-30°C
• SMILES string: O=C1CC[C@@]2([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)C(=O)C)(CC3)C)CCC2=C1)C
• InChI: 1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
• InChI key: RJKFOVLPORLFTN-LEKSSAKUSA-N

Description

General description

Steroid hormone secreted by the corpus luteum during the latter half of the menstrual cycle. Binds to the progesterone receptor in the nucleus to influence transcription. Used as a contraceptive agent and in the treatment of uterine disorders.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Binds to the progesterone receptor in the nucleus to influence transcription

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Carcinogenic / Teratogenic (D)

Reconstitution

Following reconstitution, refrigerate (4°C). Ethanol stock solutions are stable for up to 6 months at 4°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H351,H360FD,H362
• Precautionary Statements: P202 - P260 - P263 - P264 - P280 - P308 + P313
• Hazard Classifications: Carc. 2 - Lact. - Repr. 1A
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable