11074440001

Penicillin-Streptomycin

suitable for cell culture, lyophilized (clear, colorless solution after reconstitution), non-sterile; 0.2 μm filtered, sufficient for 20 mL

• Synonym(s): antibiotic
• UNSPSC Code: 12352207

Properties

• sterility: non-sterile; 0.2 μm filtered
• Quality Level: 100
• form: lyophilized (clear, colorless solution after reconstitution)
• usage: sufficient for 20 mL
• manufacturer/tradename: Roche
• concentration: 50 mg/mL streptomycin in 0.9% NaCl (as sulfate); 50,000 U/mL penicillin in 0.9% NaCl
• technique(s): cell culture | mammalian: suitable
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria
• Mode of action: cell wall synthesis | interferes; protein synthesis | interferes
• storage temp.: 2-8°C

Description

General description

Cytotoxic concentration: 10,000 IU/ml penicillin, 20 mg/ml streptomycin

Penicillin (Penicillin G) inhibits bacterial growth by inhibiting peptidoglycan synthesis. Streptomycin belongs to the family of aminoglycoside antibiotics, and inhibits bacterial growth by inhibiting protein synthesis. Penicillin-Streptomycin is used for the prevention and elimination of bacterial contaminants in cell culture.

Penicillin G, sodium salt; streptomycin sulfate
Sensitive organisms:

• Gram-positive bacteria (penicillin)
• Gram-negative bacteria (streptomycin)
• Stability:Penicillin: 3 days
• Streptomycin: 3 days in media at +37 °C

Application

Penicillin-Streptomycin has been used for the prevention and elimination of bacterial contaminants in cell culture.

Physical form

Lyophilizate, 50,000 U/ml penicillin G and 50 mg/ml streptomycin (as sulfate) in 0.9% NaCl

Preparation Note

Working concentration: 100 IU/ml penicillin
100 μg/ml streptomycin

Reconstitution

Dissolve in 20mL distilled water.

Other Notes

For life science research only. Not for use in diagnostic procedures.

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H317,H334,H361d
• Precautionary Statements: P201 - P261 - P264 - P280 - P304 + P340 - P342 + P311
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2 - Resp. Sens. 1 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): does not flash
• Flash Point(C): does not flash