8.52100

Fmoc-Lys(biotinyl-ε-aminocaproyl)-OH

Novabiochem^®

• Synonym(s): Fmoc-Lys(biotinyl-ε-aminocaproyl)-OH, N-α-Fmoc-N-ε-(biotinylcaproyl)-L-lysine
• Empirical Formula (Hill Notation): C₃₇H₄₉N₅O₇S
• CAS Number: 160158-05-4
• Molecular Weight: 707.88
• MDL number: MFCD00672325
• UNSPSC Code: 12352209
• NACRES: NA.22

Properties

• Quality Level: 200
• product line: Novabiochem^®
• Assay: ≥90.0% (HPLC); ≥98% (TLC)
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• functional group: biotin
• storage temp.: 2-30°C
• SMILES string: S1[C@H]([C@H]5NC(=O)N[C@H]5C1)CCCCC(=O)NCCCCCC(=O)NCCCC[C@H](NC(=O)OCC2c3c(cccc3)c4c2cccc4)C(=O)O
• InChI: 1S/C37H49N5O7S/c43-32(18-2-1-10-20-38-33(44)19-8-7-17-31-34-30(23-50-31)40-36(47)42-34)39-21-11-9-16-29(35(45)46)41-37(48)49-22-28-26-14-5-3-12-24(26)25-13-4-6-15-27(25)28/h3-6,12-15,28-31,34H,1-2,7-11,16-23H2,(H,38,44)(H,39,43)(H,41,48)(H,45,46)(H2,40,42
• InChI key: SLWMKSMUFPMDKA-MEROQGEASA-N

Description

General description

A modified lysine derivative for the preparation of biotin-labeled peptides by Fmoc SPPS, in which the biotin is separated from the lysine side-chain by a 6 C-atom spacer.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Biotinylation Reagents for Peptide Synthesis

Linkage

Replaces: 04-12-1243

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): +11.5 - +16.0 °
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 90.0 % (a/a)
Solubility (100mg in 10 ml DMF): clearly soluble
This product can obtain up to 10% DMF in order to assure an ideal solubility.

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable