27815

p-Toluenesulfonic acid monohydrate

≥99% (calc. to H₂O free subst.)

• Synonym(s): 4-Methylbenzenesulfonic acid monohydrate, 4-Toluenesulfonic acid monohydrate, PTSA monohydrate, TsOH monohydrate
• Linear Formula: CH₃C₆H₅SO₃H · H₂O
• CAS Number: 6192-52-5
• Molecular Weight: 190.22
• Colour Index Number: 42655
• Beilstein: 3568023
• EC Number: 203-180-0
• MDL number: MFCD00142137
• UNSPSC Code: 12352106
• PubChem Substance ID: 57648235
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: ≥99% (calc. to H₂O free subst.)
• form: solid
• impurities: ≥85% toluene-4-solfonic acid; 8-12% water (Karl Fischer)
• ign. residue: ≤0.5%
• SMILES string: O.Cc1ccc(cc1)S(O)(=O)=O
• InChI: 1S/C7H8O3S.H2O/c1-6-2-4-7(5-3-6)11(8,9)10;/h2-5H,1H3,(H,8,9,10);1H2
• InChI key: KJIFKLIQANRMOU-UHFFFAOYSA-N

Description

General description

p-Toluenesulfonic acid monohydrate, an oxonium salt, is an inexpensive and easy-to-handle organic catalyst used in organic synthesis.

Application

p-Toluenesulfonic acid monohydrate is a catalyst in esterification, reductive amination, Biginelli reaction, and intermolecular coupling of the aromatic nucleus. It is also used in the preparation of various bioactive compounds via multicomponent condensation reactions.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H314,H335
• Precautionary Statements: P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1C - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable