SBR00086

Remdesivir

≥98% (HPLC), powder

• Empirical Formula (Hill Notation): C₂₇H₃₅N₆O₈P
• CAS Number: 1809249-37-3
• Molecular Weight: 602.58
• UNSPSC Code: 51101500

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• antibiotic activity spectrum: viruses
• Mode of action: DNA synthesis | inhibits
• shipped in: ambient
• SMILES string: CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@H]([C@H]([C@](O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4
• InChI: 1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,32,37)(H2,29,30,31)/t17-,21+,23+,24+,27-,42-/m0/s1
• InChI key: RWWYLEGWBNMMLJ-YSOARWBDSA-N

Description

General description

Remdesiviris is an antibioitic which belongs to the class of compounds known as nucleotide analogues. Remdesivir has broad spectrum antiviral activity against RNA viruses.

Biochem/physiol Actions

Remdesivir inhibits viral RNA synthesis, which is essential for the replication of RNA viruses. Remdesivir is a nucleotide analogue, which means that it is designed to mimic the structure of natural nucleotides, the building blocks of RNA and DNA. When remdesivir is incorporated into the viral RNA by the viral RNA polymerase, it terminates RNA synthesis prematurely, preventing further replication of the viral RNA. This leads to the inhibition of viral replication and the reduction of viral load, which can help to reduce the severity of viral infections. Remdesivir has been shown to be active against a broad range of RNA viruses, including coronaviruses, filoviruses, and paramyxoviruses, among others.

Safety Information

• Pictograms: GHS08
• Signal Word: Warning
• Hazard Statements: H373
• Precautionary Statements: P260 - P314 - P501
• Hazard Classifications: STOT RE 2 Oral
• Target Organs: Kidney
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3