SAB2900429

Anti-GPR35 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): G protein-coupled receptor 35, G-protein coupled receptor 35, GPR35, KYNA receptor, Kynurenic acid receptor
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): immunohistochemistry: 1.25-2.5 μg/mL
• UniProt accession no.: Q9HC97
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... GPR35(2859)

Description

General description

ARTS1/Adipocyte-derived leucine aminopeptidase (A-LAP) is a member of the M1 family of zinc metallopeptidases. A-LAP is upregulatable by gamma interferon and trims N-terminal lysine, leucine, tyrosine and asparagines residues when they are not followed by proline in the ER to yield the optimal octamer, primarily and nonamer peptides for antigen presentation by major histocompatibility complex (MHC) molecules. It may also play a role in the inactivation of peptide hormones and may be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.

Immunogen

Synthetic 18 amino acid peptide from 3rd extracellular domain of human GPR35. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey (83%).

Features and Benefits

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Physical form

Solution in phosphate-buffered saline containing less than 0.1% sodium azide.

Supplied at 1 mg/ml

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable