PLA0247

Rabbit anti-ARID4B Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonym(s): 180 kDa Sin3-associated polypeptide, ARID domain-containing protein 4B, AT rich interactive domain 4B (RBP1- like), AT rich interactive domain 4B (RBP1-like), BCAA, BRCAA1, RBBP1L1, RBP1L1, Rb-binding protein homolog, SAP180, SIN3A-associated protein 180, breast cancer-associated antigen 1, breast cancer-associated antigen BRCAA1, breast carcinoma-associated antigen, histone deacetylase complex subunit SAP180, retinoblastoma binding protein 1-like 1, retinoblastoma-binding protein 1-like 1, sin3-associated polypeptide p180
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• species reactivity: human
• technique(s): immunohistochemistry: 1:1,000- 1:5,000; immunoprecipitation (IP): 5-10 μg/mg; western blot: 1:2,000- 1:10,000
• accession no.: NP_057458.4
• UniProt accession no.: Q4LE39
• shipped in: wet ice
• storage temp.: 2-8°C
• Gene Information: rabbit ... ARID4B(51742)

Description

Immunogen

The epitope recognized by PLA0247 maps to a region between residue 125 and 175 of human AT rich interactive domain 4B using the numbering given in entry NP_057458.4 (GeneID 51742).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

ARID4B (AT-rich interactive domain-containing protein 4B) is also known as RbBP1L1 (retinoblastoma binding protein 1-like 1) and is a retinoblastoma binding protein and member of the AT-rich interaction domain (ARID) family of proteins. In addition to the ARID DNA binding domain, ARID4B also contains a chromo domain and a TUDOR domain, indicating a function in chromatin organization and protein-protein interactions with methylated protein substrates. As a subunit of the SIN3A transcriptional co-repressor, ARID4B is implicated to be involved in chromatin remodeling and epigenetic modifications. ARID4B may play a role in the pathogenesis of breast cancer and other malignancies.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable