MABN824

Anti-α-Synuclein (SNCA) Antibody

mouse monoclonal, LB509

• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• Product Name: Anti-α-syn Antibody (amino acids 115-122), clone LB509,
• antibody form: purified antibody
• Quality Level: 300
• clone: LB509; monoclonal
• purified by: using protein G
• species reactivity: human, mouse
• concentration: (Please refer to lot specific datasheet.)
• technique(s): immunohistochemistry: suitable; western blot: suitable
• isotype: IgG1κ
• UniProt accession no.: P37840

Description

General description

Conjugated linear peptide corresponding to human α-syn (aa 115-122).

Specificity

This antibody detects a-Synuclein preformed fibrils that can cross seed tau fibrilliation.

Application

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected α-syn in human cerebral cortex tissue.
Western Blotting Analysis: A representative lot detected α-syn in PK-digested FL a-syn pffs (Guo, J.L., et al. (2013). Cell. 154:103-117).

Quality

Evaluated by Western Blotting in human brain tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected α-syn in 10 µg of human brain tissue lysate.

Physical properties

~15 kDa observed

Physical form

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable